Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 14/20 | 0.85 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.85 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.85 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.85 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.85 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.85 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.85 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.85 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sb-431542 SCHEMBL30033986 | 1.00 | TGFBR1 (0.85) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL155156 | 1.00 | TGFBR1 (0.85) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL21046666 | 0.99 | TGFBR1 (0.84) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29504865 | 0.99 | TGFBR1 (0.84) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| SCHEMBL22857113 | 0.94 | TGFBR1 (0.85) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29359059 | 0.92 | TGFBR1 (1.00) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29381798 | 0.92 | TGFBR1 (1.00) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL310028 | 0.92 | TGFBR1 (1.00) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL2681356 | 0.91 | TGFBR1 (0.98) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29432843 | 0.91 | TGFBR1 (0.98) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6387 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747363-A1 | NEURAL DIFFERENTIATION FROM PLURIPOTENT CELLS | Treefrog Therapeutics (FR) | 2026-05-27 | — | — | EP | claimed |
| CN-122080237-A | Preparation method of ovarian stem cells and application of ovarian stem cells in preparation of ovarian anti-aging drugs | — | 2026-05-26 | — | — | CN | claimed |
| CN-113633663-B | Application of EPC derived from induced pluripotent stem cell differentiation in preparation of cerebral apoplexy therapeutic agent | Chengnuo regenerative medical technology (Beijing) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122070916-A | Application of arteannuin with double functions in promoting liver cell maturation and relieving liver lipid metabolism dysfunction | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-22 | — | — | CN | claimed |
| WO-2026103625-A1 | METHOD FOR CONSTRUCTING THYMUS ORGANOID AND USE THEREOF | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-21 | — | — | WO | claimed |
| WO-2026106780-A1 | PHYSIOLOGICAL AGING AND REJUVENATION OF VITAL HUMAN ORGAN SYSTEMS IN VITRO | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-05-21 | — | — | WO | claimed |
| CN-116355836-B | Bile duct trunk cell expansion or passage system and application thereof | 上海市东方医院（同济大学附属东方医院） | 2026-05-19 | — | — | CN | claimed |
| CN-119614476-B | Construction method and application of thymus organoids | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-15 | — | — | CN | claimed |
| CN-121109298-B | Serum-free induction medium and induction method for promoting differentiation of mesenchymal stem cells into dermal papilla cells | 成都云测医学生物技术有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122038284-A | Method for inducing differentiation of anterior foregut endoderm cells to form lung progenitor cells and application thereof | 广州国家实验室 | 2026-05-15 | — | — | CN | claimed |
| CN-113388580-B | Method for inducing adipose-derived stem cells to differentiate into functional dopaminergic neurons and application | 中国医学科学院医学实验动物研究所 | 2022-02-18 | — | — | CN | claimed |
| CN-114072163-A | New material for healing skin wound and preventing scar | 芝加哥大学 | 2022-02-18 | — | — | CN | claimed |
| CN-111500526-B | Composition for in-vitro culture of primary mouse corneal epithelial cells and application thereof | 厦门大学 | 2022-02-18 | — | — | CN | claimed |
| EP-3954759-A1 | USE OF SMALL MOLECULES TO ENHANCE MAFA EXPRESSION IN PANCREATIC ENDOCRINE CELLS | Janssen Biotech, Inc. (US) | 2022-02-16 | — | — | EP | claimed |
| EP-3947639-A1 | METHODS OF PROMOTING THYMIC EPITHELIAL CELL AND THYMIC EPITHELIAL CELL PROGENITOR DIFFERENTIATION OF PLURIPOTENT STEM CELLS | The Trustees of Columbia University in the City of New York (US) | 2022-02-09 | — | — | EP | claimed |
| US-20220034908-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING FABRY DISEASE, CONTAINING TSP1 PROTEIN INHIBITOR AS ACTIVE INGREDIENT | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-02-03 | — | — | US | claimed |
| US-20220033773-A1 | DERIVATION OF HUMAN MICROGLIA FROM PLURIPOTENT STEM CELLS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2022-02-03 | — | — | US | claimed |
| US-20220025330-A1 | COMPOSITIONS AND METHODS FOR GENERATING HEMATOPOIETIC STEM CELLS (HSCS) | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2022-01-27 | — | — | US | claimed |
| US-20220025324-A1 | METHODS OF PRODUCING VENOUS ANGIOBLASTS AND SINUSOIDAL ENDOTHELIAL CELL-LIKE CELLS AND COMPOSITIONS THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2022-01-27 | — | — | US | claimed |
| EP-3942018-A1 | DIRECT REPROGRAMMING OF CARDIAC FIBROBLASTS INTO CARDIOMYOCYTES USING AN ENDOTHELIAL CELL TRANSDIFFERENTIATION STRATEGY | Baylor College of Medicine (US) | 2022-01-26 | — | — | EP | claimed |