Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 14/20 | 0.85 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.85 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.85 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.85 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.85 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.85 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.85 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.85 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sb-431542 SCHEMBL155156 | 1.00 | TGFBR1 (0.85) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29353092 | 1.00 | TGFBR1 (0.85) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL21046666 | 0.99 | TGFBR1 (0.84) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29504865 | 0.99 | TGFBR1 (0.84) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| SCHEMBL22857113 | 0.94 | TGFBR1 (0.85) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29359059 | 0.92 | TGFBR1 (1.00) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29381798 | 0.92 | TGFBR1 (1.00) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL310028 | 0.92 | TGFBR1 (1.00) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL2681356 | 0.91 | TGFBR1 (0.98) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B | |
| Sb-431542 SCHEMBL29432843 | 0.91 | TGFBR1 (0.98) | TGFBR1CSNK1A1CSNK1DCSNK1EACVR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250130-A2 | COMPOSITIONS AND METHODS INVOLVING ADGRG6 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-12-28 | — | — | WO | claimed |
| CN-112996906-B | Method for producing brain-like organ, brain-like organ and use thereof | JSR株式会社 | 2025-03-28 | — | — | CN | disclosed |
| CN-111386336-B | Method for preparing cell mass comprising pituitary tissue and cell mass | 住友化学株式会社 | 2025-01-17 | — | — | CN | disclosed |
| CN-113564123-B | Preparation method of nerve tissue | 住友制药株式会社 | 2024-11-15 | — | — | CN | disclosed |
| CN-111788303-B | Cell aggregate, mixture of cell aggregates, and method for producing same | 住友制药株式会社 | 2024-11-05 | — | — | CN | disclosed |
| CN-111386338-B | Method for producing a cell mass comprising cells of the nervous system or a nervous tissue and a non-neuroepithelial tissue, and cell mass | 住友化学株式会社 | 2024-10-08 | — | — | CN | disclosed |
| WO-2023250130-A2 | COMPOSITIONS AND METHODS INVOLVING ADGRG6 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-12-28 | — | — | WO | disclosed |
| CN-109312306-B | Method for producing retinal tissue | 住友制药株式会社 | 2023-05-09 | — | — | CN | disclosed |
| EP-4110465-A1 | MOLECULAR BIOMARKERS AND TARGETS FOR FUCHS' ENDOTHELIAL CORNEAL DYSTROPHY AND GLAUCOMA | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-109072198-B | Preparation method of dopamine-producing neural progenitor cells | 国立大学法人京都大学 | 2022-08-26 | — | — | CN | disclosed |