Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353417 | 0.78 | LMNA (0.46) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL28678768 | 0.78 | LMNA (0.46) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL28296390 | 0.77 | HRH4 (0.38) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL30059715 | 0.75 | HTR2C (0.54) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL29310292 | 0.66 | ALDH1A1 (0.36) | LMNAHRH3KCNH2CASP1 | |
| SCHEMBL29310289 | 0.66 | ALDH1A1 (0.36) | HRH3KCNH2HTR2AHTR2C | |
| SCHEMBL2421661 | 0.65 | HRH4 (0.45) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL24053385 | 0.64 | LMNA (0.38) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL30059728 | 0.64 | MAPT (0.50) | LMNAHTR2AHTR2COPRL1 | |
| SCHEMBL10774710 | 0.64 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968857-A | Isochrysine analogue prepared from enoxacin as raw material and preparation method and application thereof | 郑州工业应用技术学院 | 2022-01-25 | — | — | CN | claimed |
| CN-113968857-A | Isochrysine analogue prepared from enoxacin as raw material and preparation method and application thereof | 郑州工业应用技术学院 | 2022-01-25 | — | — | CN | disclosed |