Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 8/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776444 | 0.78 | CYP2C9 (0.37) | HRH4KCNH2LMNACYP2C9ATP6V1B2 | |
| SCHEMBL29353387 | 0.77 | LMNA (0.43) | HRH4HRH3KCNH2HTR2CHTR2A | |
| SCHEMBL28873005 | 0.76 | MAPT (0.44) | HTR2CHTR2AHTR2BLMNACYP2C9 | |
| SCHEMBL30059715 | 0.75 | HTR2C (0.54) | HRH4KCNH2HTR2CHTR2ALMNA | |
| SCHEMBL2421661 | 0.68 | HRH4 (0.45) | HRH4HRH3KCNH2LMNACYP2C9 | |
| SCHEMBL30059728 | 0.64 | MAPT (0.50) | HTR2CHTR2AHTR2BLMNA | |
| SCHEMBL6225002 | 0.62 | HTR6 (0.54) | KCNH2HTR2CHTR2AHTR2B | |
| SCHEMBL24053385 | 0.61 | LMNA (0.38) | HRH4KCNH2HTR2CLMNACYP2C9 | |
| SCHEMBL2422635 | 0.60 | EPHX2 (0.41) | KCNH2HTR2C | |
| SCHEMBL5871769 | 0.60 | HTR2C (0.58) | KCNH2HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776411-A | Mustargen Carbostyril derivative and its preparation method and application | 石家庄学院 | 2019-05-21 | — | — | CN | disclosed |