Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.77 |
| ▸ | CLK1 | P49759 | 4/20 | 0.70 |
| ▸ | CLK2 | P49760 | 4/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.70 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.70 |
| ▸ | CLK3 | P49761 | 3/20 | 0.70 |
| ▸ | GSK3B | P49841 | 2/20 | 0.70 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.70 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.70 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.70 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.70 |
| ▸ | PIM1 | P11309 | 2/20 | 0.63 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.63 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758312 | 1.00 | FGFR1 (0.77) | FGFR1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL16935421 | 0.87 | FGFR1 (1.00) | FGFR1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL2455100 | 0.82 | GSK3B (1.00) | FGFR1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL1422720 | 0.82 | NPC1 (0.66) | FGFR1ALDH1A1 | |
| SCHEMBL4791316 | 0.81 | CLK1 (1.00) | FGFR1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL26260198 | 0.78 | CYP11B2 (0.88) | FGFR1CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL14688781 | 0.78 | PIM1 (1.00) | FGFR1CLK2DYRK1ACLK3PIM1 | |
| SCHEMBL15651609 | 0.77 | MAPK1 (0.71) | FGFR1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL27074803 | 0.77 | GSK3B (0.70) | FGFR1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL6657347 | 0.77 | NPC1 (0.64) | FGFR1CYP11B1CYP11B2CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968859-B | Multi-element condensed ring compound and application thereof in organic electroluminescent device | 北京鼎材科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-113968859-A | Multi-element fused ring compound and application thereof in organic electroluminescent device | 北京鼎材科技有限公司 | 2022-01-25 | — | — | CN | disclosed |