Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28274500 | 0.84 | AHR (0.46) | PTGS2PTGS1 | |
| SCHEMBL8181096 | 0.80 | SIGMAR1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL30273027 | 0.77 | HSD17B1 (0.42) | — | |
| SCHEMBL14010787 | 0.76 | MAPK14 (0.34) | PTGS2PTGS1 | |
| SCHEMBL29327032 | 0.76 | HTR2C (0.46) | — | |
| SCHEMBL28084701 | 0.73 | PTGES (0.34) | — | |
| SCHEMBL13139758 | 0.72 | CHRNB4 (0.40) | NISCH | |
| SCHEMBL25615298 | 0.71 | CHUK (0.40) | PTGS2PTGS1 | |
| SCHEMBL15517645 | 0.70 | NISCH (0.49) | NISCHPTGS2PTGS1TDP2ERCC1 | |
| SCHEMBL15384336 | 0.70 | CYP3A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941921-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | Arbutus Biopharma Corporation (CA) | 2022-01-26 | — | — | EP | disclosed |