Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358930 | 0.87 | RAB9A (0.46) | TSHRALDH1A1KDM4EHPGDGAA | |
| SCHEMBL21384077 | 0.82 | CCNE1 (0.49) | ALDH1A1SCDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21395005 | 0.82 | CCNE1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10SCD | |
| SCHEMBL29357987 | 0.82 | CCNE1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10SCD | |
| SCHEMBL29358368 | 0.75 | L3MBTL1 (0.45) | TSHRALDH1A1KDM4EHPGDGAA | |
| SCHEMBL34467367 | 0.71 | CDK2 (0.47) | ALDH1A1SCDSMN1; SMN2CCNE1CDK2 | |
| SCHEMBL5502790 | 0.70 | SMN1; SMN2 (0.47) | TSHRGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2654505 | 0.70 | L3MBTL1 (0.59) | TSHRALDH1A1KDM4EHPGDGAA | |
| SCHEMBL29353713 | 0.70 | SMN1; SMN2 (0.64) | TSHRALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL29356285 | 0.70 | TSHR (0.50) | TSHRALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |