Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357529 | 0.90 | NQO2 (0.38) | NQO2ALDH1A1TP53GLAMAPT | |
| SCHEMBL19742480 | 0.85 | MTNR1B (0.36) | MTNR1B | |
| SCHEMBL29357462 | 0.84 | ACACB (0.35) | ACACBNQO2CA1CA2CA12 | |
| SCHEMBL29356098 | 0.83 | MAOB (0.47) | NQO2CA1CA2CA12CA9 | |
| SCHEMBL4128683 | 0.78 | HTR2C (0.40) | ACACBMAOBACACA | |
| SCHEMBL4128684 | 0.78 | HTR2C (0.40) | ACACBMAOBACACA | |
| SCHEMBL29357460 | 0.76 | KDM4A (0.41) | NQO2ALDH1A1TP53GLAMAPT | |
| SCHEMBL19742695 | 0.76 | MTNR1A (0.32) | MTNR1B | |
| SCHEMBL4126397 | 0.75 | DRD2 (0.41) | ACACBMAOBACACAMTNR1B | |
| SCHEMBL4126395 | 0.75 | DRD2 (0.41) | ACACBMAOBACACAMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | disclosed |