Sugi Predict

Sugi Predict / Compounds / SCHEMBL29357079

SCHEMBL29357079

SCHEMBL29357079

NC(=O)NCCC[C@H](N)C(=O)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.42
▸ OTC P00480 1/20 0.41
▸ DDAH1 O94760 3/20 0.39
▸ GNAI3 P08754 1/20 0.37
▸ GNAO1 P09471 1/20 0.37
▸ GNAI1 P63096 1/20 0.37
▸ ARG1 P05089 1/20 0.36
▸ RRM1 P23921 1/20 0.35
▸ C3AR1 Q16581 1/20 0.34
▸ ANPEP P15144 2/20 0.33
▸ RNPEP Q9H4A4 2/20 0.33
▸ DNPEP Q9ULA0 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ NOS1 P29475 1/20 0.33
▸ CYP1A2 P05177 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ APEX1 P27695 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10483768 0.85 DPP7 (0.40) DPP7OTCDDAH1GNAI3GNAO1
SCHEMBL31198211 0.85 DPP7 (0.40) DPP7OTCDDAH1GNAI3GNAO1
SCHEMBL3169670 0.83 DPP7 (0.44) DPP7OTCDDAH1GNAI3GNAO1
SCHEMBL607463 0.83 DPP7 (0.44) DPP7OTCDDAH1GNAI3GNAO1
SCHEMBL18866881 0.83 DPP7 (0.44) DPP7OTCDDAH1GNAI3GNAO1
L-Citrulline SCHEMBL215403 0.82 OTC (0.59) OTCDDAH1ARG1NOS1CYP1A2
L-Citrulline SCHEMBL437142 0.82 OTC (0.59) OTCDDAH1ARG1NOS1CYP1A2
L-Citrulline SCHEMBL15909604 0.82 OTC (0.59) OTCDDAH1ARG1NOS1CYP1A2
L-Citrulline SCHEMBL22426116 0.82 OTC (0.59) OTCDDAH1ARG1NOS1CYP1A2
L-Citrulline SCHEMBL9070200 0.82 OTC (0.59) OTCDDAH1ARG1NOS1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746916-A2 CLEAVABLE POLYMER-DRUG CONJUGATES FOR ALZHEIMER'S DISEASE University of Utah Research Foundation (US) 2026-05-27 — — EP disclosed
WO-2025024343-A2 CLEAVABLE POLYMER-DRUG CONJUGATES FOR ALZHEIMER'S DISEASE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-01-30 — — WO disclosed
US-12173086-B2 Alpha-v beta-6 integrin ligands and uses thereof Arrowhead Pharmaceuticals, Inc. (US) 2024-12-24 — — US disclosed
CN-115044623-A Enzymatic synthesis process of isocitric acid 长兴制药股份有限公司 2022-09-13 — — CN disclosed
EP-3981780-A1 ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF Arrowhead Pharmaceuticals, Inc. (US) 2022-04-13 — — EP disclosed
US-20220024975-A1 ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024975-A1 ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF ITGAV, ITGA6, ITGB6 DPP7 2508/4885OTC 4780/4885DDAH1 4706/4885
US-12173086-B2 Alpha-v beta-6 integrin ligands and uses thereof ITGAV, ITGA6, ITGB6 DPP7 2508/4885OTC 4780/4885DDAH1 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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