Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CASP1 | P29466 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241936 | 1.00 | MAPT (0.69) | MAPTLMNABAZ2BTRPV1TAAR1 | |
| Acetic Acid SCHEMBL8714196 | 0.96 | MAPT (0.68) | MAPTLMNABAZ2BTRPV1TAAR1 | |
| SCHEMBL4540180 | 0.93 | MAPT (0.59) | MAPTLMNABAZ2BTRPV1TAAR1 | |
| SCHEMBL6474214 | 0.91 | LMNA (0.60) | MAPTLMNABAZ2BTRPV1TAAR1 | |
| SCHEMBL350201 | 0.90 | TRPV1 (0.69) | MAPTLMNABAZ2BTRPV1FAAH | |
| SCHEMBL21154454 | 0.89 | LMNA (0.55) | MAPTLMNABAZ2BTRPV1KMT2A | |
| Acetic Acid SCHEMBL8718251 | 0.87 | TRPV1 (0.68) | MAPTLMNABAZ2BTRPV1FAAH | |
| SCHEMBL24405315 | 0.86 | MAPT (0.74) | MAPTLMNABAZ2BTRPV1TAAR1 | |
| SCHEMBL24914458 | 0.86 | MTHFD2 (0.60) | MAPTLMNABAZ2BTRPV1FAAH | |
| SCHEMBL31117573 | 0.86 | LMNA (0.55) | MAPTLMNABAZ2BTRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025041160-A1 | BIFUNCTIONAL CONJUGATE MOLECULES FOR CANCER TREATMENT AND PROCESS OF MAKING THE SAME | BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE (BITS), PILANI (IN) | 2025-02-27 | — | — | WO | disclosed |
| CN-113121527-B | Tricyclic compounds and uses thereof | 上海辉启生物医药科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| CN-109928971-B | Aryl substituted aminotetrahydropyrans and uses thereof | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-111757882-B | Compounds for treating, alleviating or preventing conditions associated with tau aggregates | AC免疫有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022194087-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-09-22 | — | — | WO | disclosed |
| EP-3941477-A1 | NOVEL COMPOUNDS FOR THE TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES | AC Immune SA (CH) | 2022-01-26 | — | — | EP | disclosed |