Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376518 | 0.65 | KDM5A (0.55) | KDM5AKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL826541 | 0.62 | KDM5A (0.58) | KDM5AKDM4EALDH1A1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL31236648 | 0.62 | KDM5A (0.98) | KDM5AKDM5B | |
| SCHEMBL6642827 | 0.61 | KDM5A (0.50) | KDM5AKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL187437 | 0.54 | DPYD (0.64) | KDM4EALDH1A1 | |
| SCHEMBL31153943 | 0.54 | PLAT (0.45) | KDM5AKDM4EALDH1A1 | |
| SCHEMBL29118313 | 0.50 | — | — | |
| SCHEMBL3825045 | 0.49 | CHUK (0.45) | KDM4EALDH1A1 | |
| SCHEMBL12342961 | 0.49 | KMT2A (0.51) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL189451 | 0.49 | DPYD (1.00) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | disclosed |