Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 2/20 | 0.64 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23622043 | 0.79 | DPYD (0.64) | DPYDKDM3BKDM4EALDH1A1KMT2A | |
| SCHEMBL189451 | 0.78 | DPYD (1.00) | DPYDMCL1KDM4EALDH1A1NPSR1 | |
| SCHEMBL309065 | 0.76 | KDM3B (0.43) | DPYDKDM3BKMT2ATDP1MEN1 | |
| SCHEMBL8508879 | 0.72 | KMT2A (0.41) | DPYDKDM3BKMT2ATDP1MEN1 | |
| SCHEMBL3321070 | 0.67 | — | — | |
| SCHEMBL11739894 | 0.67 | — | — | |
| SCHEMBL25418259 | 0.67 | ATAD2 (0.60) | KDM3BKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL1404492 | 0.67 | — | — | |
| SCHEMBL10509279 | 0.67 | — | — | |
| SCHEMBL25450 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250277257-A1 | HYBRIDIZATION COMPOSITIONS AND METHODS | DAKO DENMARK APS (DK) | 2025-09-04 | — | — | US | claimed |
| US-12209276-B2 | Hybridization compositions and methods | AGILENT TECHNOLOGIES, INC. (US) | 2025-01-28 | — | — | US | claimed |
| US-20240124922-A1 | HYBRIDIZATION COMPOSITIONS AND METHODS | DAKO DENMARK APS (DK) | 2024-04-18 | — | — | US | claimed |
| US-11834703-B2 | Hybridization compositions and methods | AGILENT TECHNOLOGIES, INC. (US) | 2023-12-05 | — | — | US | claimed |
| US-20220162683-A1 | COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH NO DENATURATION | DAKO DENMARK APS (DK) | 2022-05-26 | — | — | US | claimed |
| US-20220154263-A1 | COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH SEPARATE DENATURATION OF THE SAMPLE AND PROBE | DAKO DENMARK APS (DK) | 2022-05-19 | — | — | US | claimed |
| US-20220064716-A1 | HYBRIDIZATION COMPOSITIONS AND METHODS | DAKO DENMARK APS (DK) | 2022-03-03 | — | — | US | claimed |
| CN-107574230-B | Compositions and methods for performing hybridization with separate denaturation of sample and probe | 安捷伦科技有限公司 | 2022-01-11 | — | — | CN | claimed |
| US-11118214-B2 | Hybridization compositions and methods | AGILENT TECHNOLOGIES, INC. (US) | 2021-09-14 | — | — | US | claimed |
| EP-3733871-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF CHROMOSOMAL ABERRATIONS WITH NOVEL HYBRIDIZATION BUFFERS | Dako Denmark A/S (DK) | 2020-11-04 | — | — | EP | claimed |
| US-20110281263-A1 | Compositions and Methods for Detection of Chromosomal Aberrations with Novel Hybridization Buffers | DAKO DENMARK APS (DK) | 2011-11-17 | — | — | US | claimed |
| US-20110229975-A1 | Hybridization Compositions and Methods | DAKO DENMARK APS (DK) | 2011-09-22 | — | — | US | claimed |
| WO-2011067678-A2 | COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH NO DENATURATION | MATTHIESEN STEEN H (DK) | 2011-06-09 | — | — | WO | claimed |
| EP-2285982-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF CHROMOSOMAL ABERRATIONS WITH NOVEL HYBRIDIZATION BUFFERS | Dako Denmark A/S (DK) | 2011-02-23 | — | — | EP | claimed |
| EP-2285979-A1 | HYBRIDIZATION COMPOSITIONS AND METHODS | Dako Denmark A/S (DK) | 2011-02-23 | — | — | EP | claimed |
| WO-2010097656-A1 | COMPOSITIONS AND METHODS FOR PERFORMING A STRINGENT WASH STEP IN HYBRIDIZATION APPLICATIONS | DAKO DENMARK A/S (DK) | 2010-09-02 | — | — | WO | claimed |
| WO-2010097655-A1 | COMPOSITIONS AND METHODS FOR RNA HYBRIDIZATION APPLICATIONS | DAKO DENMARK A/S (DK) | 2010-09-02 | — | — | WO | claimed |
| WO-2010097707-A1 | COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH SEPARATE DENATURATION OF THE SAMPLE AND PROBE | DAKO DENMARK A/S (DK) | 2010-09-02 | — | — | WO | claimed |
| WO-2009147537-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF CHROMOSOMAL ABERRATIONS WITH NOVEL HYBRIDIZATION BUFFERS | DAKO DENMARK A/S (DK) | 2009-12-10 | — | — | WO | claimed |
| WO-2009144581-A1 | HYBRIDIZATION COMPOSITIONS AND METHODS | DAKO DENMARK A/S (DK) | 2009-12-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229975-A1 | Hybridization Compositions and Methods | POLRMT, POLL, POLH | DPYD 97/4885KDM3B 4294/4885MCL1 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.