Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141712 | 1.00 | TAAR1 (0.55) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL2963428 | 0.93 | TAAR1 (0.49) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL8992885 | 0.90 | HTT (0.51) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL1464785 | 0.89 | CD274 (0.50) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL7947382 | 0.82 | MMP3 (0.56) | MAPTALDH1A1PKMTSHRKMT2A | |
| SCHEMBL8249225 | 0.81 | TAAR1 (0.61) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL2119072 | 0.81 | TAAR1 (0.59) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL5966222 | 0.81 | TAAR1 (0.55) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL11082938 | 0.78 | TAAR1 (0.60) | TAAR1CYP3A4SLC6A4CYP1A2MAPT | |
| SCHEMBL1721517 | 0.78 | SLC5A2 (0.38) | TAAR1CYP3A4SLC6A4CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479801-B2 | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-g]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline-6,7-diol | H. LUNDBECK A/S (DK) | 2025-11-25 | — | — | US | disclosed |
| CN-118908964-A | Method for producing a compound | H.隆德贝克有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-113874355-B | Process for the manufacture of (6 AR,10 AR) -7-propyl-6, 6A,7,8,9, 10A, 11-octahydro- [1,3] dioxolo [4',5':5,6] benzo [1,2-G ] quinoline and (4 AR,10 AR) -1-propyl-1, 2,3, 4A,5, 10A-octahydro-benzo [ G ] quinoline-6, 7-diol | H.隆德贝克有限公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20240018107-A1 | PROCESS FOR THE MANUFACTURING OF (6AR,10AR)-7-PROPYL-6,6A,7,8,9,10,10A,11-OCTAHYDRO-[1,3]DIOXOLO[4',5':5,6]BENZO[1,2-G]QUINOLINE AND (4AR,10AR)-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDRO-BENZO[G]QUINOLINE-6,7-DIOL | H. LUNDBECK A/S (DK) | 2024-01-18 | — | — | US | disclosed |
| US-11866410-B2 | Process for the manufacturing of (6AR,10AR)-7-propyl-6,6A,7,8,9,10,10A,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4AR, 10AR)-1-propyl-1,2,3,4,4A,5,10,10A-octahydro-benzo[G]quinoline-6,7-diol | H. LUNDBECK A/S (DK) | 2024-01-09 | — | — | US | disclosed |
| US-20220024875-A1 | PROCESS FOR THE MANUFACTURING OF (6AR,10AR)-7-PROPYL-6,6A,7,8,9,10,10A,11-OCTAHYDRO-[1,3]DIOXOLO[4',5':5,6]BENZO[1,2-G]QUINOLINE AND (4AR,10AR)-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDRO-BENZO[G]QUINOLINE-6,7-DIOL | H. LUNDBECK A/S (DK) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024875-A1 | PROCESS FOR THE MANUFACTURING OF (6AR,10AR)-7-PROPYL-6,6A,7,8,9,10,10A,11-OCTAHYDRO-[1,3]DIOXOLO[4',5':5,6]BENZO[1,2-G]QUINOLINE AND (4AR,10AR)-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDRO-BENZO[G]QUINOLINE-6,7-DIOL | PARK7, SNCA, CYP1B1 | TAAR1 420/4885CYP3A4 118/4885SLC6A4 1446/4885 |
| US-11866410-B2 | Process for the manufacturing of (6AR,10AR)-7-propyl-6,6A,7,8,9,10,10A,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4AR, 10AR)-1-propyl-1,2,3,4,4A,5,10,10A-octahydro-benzo[G]quinoline-6,7-diol | PARK7, SNCA, CYP1B1 | TAAR1 416/4885CYP3A4 115/4885SLC6A4 1435/4885 |
| US-20240018107-A1 | PROCESS FOR THE MANUFACTURING OF (6AR,10AR)-7-PROPYL-6,6A,7,8,9,10,10A,11-OCTAHYDRO-[1,3]DIOXOLO[4',5':5,6]BENZO[1,2-G]QUINOLINE AND (4AR,10AR)-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDRO-BENZO[G]QUINOLINE-6,7-DIOL | PARK7, SNCA, CYP1B1 | TAAR1 434/4885CYP3A4 137/4885SLC6A4 1416/4885 |
| US-12479801-B2 | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-g]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline-6,7-diol | PARK7, SNCA, CYP1B1 | TAAR1 430/4885CYP3A4 130/4885SLC6A4 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.