Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358160 | 0.87 | GPR52 (0.43) | GPR52GRM2CYP11B1CYP11B2RPS6KB1 | |
| SCHEMBL29357073 | 0.87 | RPS6KB1 (0.45) | GPR52CYP11B1CYP11B2RPS6KB1AKT1 | |
| SCHEMBL29358037 | 0.85 | GRM2 (0.47) | GRM2CYP11B1CYP11B2RPS6KB1AKT1 | |
| SCHEMBL29357035 | 0.84 | RPS6KB1 (0.43) | GPR52GRM2CYP11B1CYP11B2RPS6KB1 | |
| SCHEMBL29356877 | 0.76 | GPR52 (0.40) | GPR52GRM2HDAC3HDAC1HDAC2 | |
| SCHEMBL29358907 | 0.75 | RPS6KB1 (0.42) | GPR52CYP11B1CYP11B2RPS6KB1AKT1 | |
| SCHEMBL29358585 | 0.75 | GPR52 (0.42) | GPR52CASP1GRM2PIK3CAHDAC3 | |
| SCHEMBL29355483 | 0.74 | GPR52 (0.42) | GPR52CASP1GRM2PIK3CAHDAC3 | |
| SCHEMBL29355505 | 0.71 | RPS6KB1 (0.43) | GPR52GRM2CYP11B1CYP11B2RPS6KB1 | |
| SCHEMBL1503063 | 0.70 | GPR52 (0.43) | GPR52CASP1PIK3CAHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |