Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357073 | 0.88 | RPS6KB1 (0.45) | RPS6KB1AKT1GPR52CD38CYP11B1 | |
| SCHEMBL29355505 | 0.80 | RPS6KB1 (0.43) | RPS6KB1AKT1GPR52CD38CYP11B1 | |
| SCHEMBL29357035 | 0.76 | RPS6KB1 (0.43) | RPS6KB1AKT1GPR52MAOBCYP11B1 | |
| SCHEMBL29358277 | 0.75 | GPR52 (0.43) | RPS6KB1AKT1GPR52CYP11B1CYP11B2 | |
| SCHEMBL29358160 | 0.74 | GPR52 (0.43) | RPS6KB1AKT1GPR52CYP11B1CYP11B2 | |
| Trifluoroacetic Acid SCHEMBL29358100 | 0.74 | RPS6KB1 (0.42) | RPS6KB1AKT1GPR52CYP11B1CYP11B2 | |
| SCHEMBL29355501 | 0.73 | GPR52 (0.41) | RPS6KB1AKT1GPR52CD38CYP11B1 | |
| SCHEMBL29356932 | 0.73 | PLA2G1B (0.41) | RPS6KB1AKT1GPR52CD38GAA | |
| SCHEMBL29355361 | 0.71 | GPR52 (0.40) | GPR52MAOBCD38CYP11B1CYP11B2 | |
| SCHEMBL21394891 | 0.70 | ALDH1A1 (0.47) | CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |