SCHEMBL29358306

SCHEMBL29358306

O=C(O)CCCc1cc2c(cc1O)Oc1cc(O)c(CCCC(=O)O)cc1C21OC(=O)c2cc(C(=O)O)ccc21.O=C(O)CCCc1cc2c(cc1O)Oc1cc(O)c(CCCC(=O)O)cc1C21OC(=O)c2ccc(C(=O)O)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
KMT2A Q03164 2/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
SMAD3 P84022 1/20 0.42
PRMT1 Q99873 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALB P02768 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
GSTP1 P09211 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31091444 0.94 FTO (0.44) FTOMEN1MAPTHTTKMT2A
SCHEMBL3146789 0.90 FTO (0.45) FTOMEN1MAPTHTTKMT2A
SCHEMBL2859711 0.90 FTO (0.42) FTOMEN1MAPTHTTKMT2A
SCHEMBL29358769 0.90 FTO (0.45) FTOMEN1MAPTHTTKMT2A
SCHEMBL4323243 0.83 FTO (0.47) FTOMEN1MAPTHTTKMT2A
SCHEMBL4318993 0.83 FTO (0.43) FTOMEN1MAPTHTTKMT2A
SCHEMBL30105431 0.83 FTO (0.46) FTOMEN1MAPTHTTKMT2A
SCHEMBL3685151 0.82 MEN1 (0.40) FTOMEN1MAPTHTTKMT2A
SCHEMBL3685707 0.82 FTO (0.43) FTOMEN1MAPTHTTKMT2A
SCHEMBL3688575 0.80 FTO (0.42) FTOMEN1MAPTHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12571798-B2 Cancer biomarkers and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-10 US disclosed
US-12332245-B2 Cancer biomarkers and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-06-17 US disclosed
EP-3941630-B1 PRECISE DELIVERY OF COMPONENTS INTO FLUIDS CELLULAR RES INC (US) 2025-04-16 EP disclosed
US-20240325487-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. 2024-10-03 US disclosed
US-20240263165-A1 Precise Delivery of Components into Fluids BECTON, DICKINSON AND COMPANY 2024-08-08 US disclosed
US-11976269-B2 Precise delivery of components into fluids CELLULAR RESEARCH, INC. (US) 2024-05-07 US disclosed
US-11965208-B2 Methods of associating phenotypical data and single cell sequencing data BECTON, DICKINSON AND COMPANY (US) 2024-04-23 US disclosed
CN-113557090-B Accurate delivery of components into a fluid 赛卢拉研究公司 2024-03-22 CN disclosed
EP-3796002-B1 CANCER BIOMARKERS AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2023-11-22 EP disclosed
US-11813304-B2 Compounds and methods for inhibiting phosphate transport ARDELYX, INC. (US) 2023-11-14 US disclosed
US-20230204591-A1 CANCER BIOMARKERS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-06-29 US disclosed
EP-3884935-B1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX INC (US) 2023-06-14 EP disclosed
CN-114404588-A Compounds and methods for inhibiting phosphate transport 阿德利克斯公司 2022-04-29 CN disclosed
EP-3941630-A1 PRECISE DELIVERY OF COMPONENTS INTO FLUIDS Cellular Research, Inc. (US) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571798-B2 Cancer biomarkers and methods of use thereof MKI67, BRCA1, CD68 FTO 4236/4885MEN1 4354/4885MAPT 2345/4885
US-20240325487-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC34A3, SLC34A2, SLC34A1 FTO 4008/4885MEN1 2203/4885MAPT 4468/4885
US-11813304-B2 Compounds and methods for inhibiting phosphate transport SLC34A3, SLC34A2, SLC34A1 FTO 4008/4885MEN1 2203/4885MAPT 4468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.