Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323243 | 0.91 | FTO (0.47) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL2859711 | 0.89 | FTO (0.42) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL3688701 | 0.87 | MAPT (0.39) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL3656489 | 0.87 | FTO (0.44) | FTOMAPTMEN1KMT2AHTT | |
| Bromide SCHEMBL23115511 | 0.86 | FTO (0.43) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL3685151 | 0.85 | MEN1 (0.40) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL31091444 | 0.85 | FTO (0.44) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL29613031 | 0.85 | FTO (0.44) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL4062067 | 0.85 | FTO (0.44) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL7610486 | 0.84 | HTT (0.46) | FTOMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507395-B2 | Methods of using fluorescent pH indicators for intracellular assays | MDS ANALYTICAL TECHNOLOGIES (US) INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-20050136503-A1 | Fluorescent pH indicators for intracellular assays | MOLECULAR DEVICES, INC. | 2005-06-23 | — | — | US | disclosed |
| US-6800765-B2 | COMPOUND FOR USE AS DIAGNOSTIC TOOL IN THE DETERMINATION OF HYDROGEN ION CONCENTRATION IN FLUIDS | MOLECULAR DEVICES CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-20030068668-A1 | Fluorescent pH indicators for intracellular assays | MOLECULAR DEVICES, INC. | 2003-04-10 | — | — | US | disclosed |
| EP-1281712-A1 | Fluorescent pH indicators for intracellular assays | Molecular Devices Corporation (US) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030068668-A1 | Fluorescent pH indicators for intracellular assays | CHERP, GOT1, NSF | FTO 2752/4885MAPT 1678/4885MEN1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.