Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384506 | 1.00 | ABCC8 (0.50) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL29356789 | 0.93 | ABCC8 (0.49) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL21394863 | 0.93 | ABCC8 (0.49) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL21394481 | 0.89 | RAB9A (0.46) | ABCC8KCNJ11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29358443 | 0.89 | RAB9A (0.46) | ABCC8KCNJ11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21394641 | 0.88 | TSHR (0.47) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL29356991 | 0.88 | TSHR (0.47) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL21384424 | 0.87 | ABCC8 (0.47) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL29356186 | 0.87 | ABCC8 (0.47) | ABCC8KCNJ11SNCANPC1RAB9A | |
| SCHEMBL21394977 | 0.86 | ABCC8 (0.43) | ABCC8KCNJ11SNCANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |