Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358443 | 1.00 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL29358498 | 0.89 | ABCC8 (0.50) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL21384506 | 0.89 | ABCC8 (0.50) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL21394760 | 0.88 | L3MBTL1 (0.47) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL29354586 | 0.88 | L3MBTL1 (0.47) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL21395180 | 0.88 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL29359042 | 0.88 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL21394625 | 0.88 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL21394720 | 0.88 | MME (0.42) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL21394980 | 0.85 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |