Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361424 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELASOS1IDO1 | |
| SCHEMBL23522417 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELASOS1IDO1 | |
| SCHEMBL23522388 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELASOS1IDO1 | |
| SCHEMBL23198998 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELASOS1IDO1 | |
| SCHEMBL23522410 | 0.80 | NFKB1 (0.45) | NFKB1NFKB2RELAIDO1 | |
| SCHEMBL23522430 | 0.77 | NFKB1 (0.35) | NFKB1NFKB2RELASOS1IDO1 | |
| Altersolanol C SCHEMBL23199105 | 0.76 | NFKB1 (0.66) | NFKB1NFKB2RELAIDO1 | |
| SCHEMBL23522371 | 0.74 | NFKB1 (0.50) | NFKB1NFKB2RELAIDO1 | |
| Alterporriol A/B SCHEMBL30948399 | 0.73 | NFKB1 (0.59) | NFKB1NFKB2RELAIDO1PIM1 | |
| SCHEMBL29360532 | 0.70 | NFKB1 (0.39) | NFKB1NFKB2RELASOS1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | disclosed |