Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080617 | 0.80 | F2 (0.56) | ALDH1A1FABP4PKMKDM4EHPGD | |
| SCHEMBL13495628 | 0.80 | ALDH1A1 (0.46) | ALDH1A1FABP4MEN1KMT2AL3MBTL1 | |
| SCHEMBL13017279 | 0.80 | FABP4 (0.46) | ALDH1A1FABP4KMT2AL3MBTL1LMNA | |
| SCHEMBL10246261 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1FABP4MEN1KMT2AFFAR4 | |
| SCHEMBL10008677 | 0.79 | FABP4 (0.48) | ALDH1A1FABP4MEN1KMT2AL3MBTL1 | |
| SCHEMBL4000323 | 0.78 | TSHR (0.40) | ALDH1A1MEN1KMT2AL3MBTL1FFAR4 | |
| SCHEMBL11440692 | 0.77 | FABP4 (0.60) | ALDH1A1FABP4MEN1KMT2AL3MBTL1 | |
| SCHEMBL6279227 | 0.77 | TSHR (0.42) | ALDH1A1L3MBTL1FFAR4TSHRHPGD | |
| SCHEMBL10118749 | 0.77 | BRD4 (0.43) | FABP4CA1CA2 | |
| SCHEMBL21569720 | 0.77 | L3MBTL1 (0.50) | ALDH1A1MEN1KMT2AL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229395-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009090054-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-07-23 | — | — | WO | disclosed |