SCHEMBL29360207

SCHEMBL29360207

COc1cccc2c1[nH]c(=S)n2Cc1c(F)cccc1F

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DAO P14920 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSP90B1 P14625 1/20 0.41
TRAP1 Q12931 1/20 0.41
KDM4E B2RXH2 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
RXFP1 Q9HBX9 2/20 0.39
PRNP P04156 2/20 0.39
GNRHR P30968 5/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PSMB8 P28062 1/20 0.38
MPO P05164 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406168 0.75 APOBEC3G (0.62) SMN1; SMN2TDP1L3MBTL1KDM4ERXFP1
SCHEMBL29533085 0.74 KDM4E (0.53) SMN1; SMN2TDP1L3MBTL1HSP90B1TRAP1
SCHEMBL29495576 0.69 PGR (0.43) SMN1; SMN2DAOTDP1L3MBTL1HSP90B1
SCHEMBL29349517 0.68 TRAP1 (0.43) MAPK1SMN1; SMN2TDP1L3MBTL1HSP90B1
SCHEMBL30118979 0.68 TRAP1 (0.43) HSP90B1TRAP1CA12CA1CA2
SCHEMBL5201125 0.68 TLR8 (0.43) MAPK1SMN1; SMN2GNRHR
SCHEMBL29366126 0.67 PGR (0.55) TDP1L3MBTL1HSP90B1TRAP1KDM4E
SCHEMBL5201559 0.66 MAPK1 (0.43) MAPK1SMN1; SMN2GNRHR
SCHEMBL5755646 0.64 GNRHR (0.59) MAPK1SMN1; SMN2GNRHR
SCHEMBL7128653 0.64 GNRHR (0.40) MAPK1SMN1; SMN2GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036906-A Recombinant protein of novel cytokine for promoting collagen regeneration, and preparation method and application thereof 四川大学华西口腔医院 2026-05-15 CN claimed
EP-4653469-A1 FUSION PROTEIN OF GE AND GI OF VARICELLA-ZOSTER VIRUS AND USE Xiamen University (CN) 2025-11-26 EP claimed
CN-115894636-B Seasonal influenza A universal Mosaic recombinant antigen, vaccine and application thereof 中山大学·深圳 2025-06-03 CN claimed
CN-119424626-A Swine fever virus subunit vaccine and preparation method thereof 巨星农牧有限公司 2025-02-14 CN claimed
CN-119372257-A Preparation method of Cap protein of parrot beak-feather disease virus 南京乾元浩生物科技有限公司 2025-01-28 CN claimed
CN-118684783-A Long-acting recombinant canine interferon alpha 2 青岛农业大学 2024-09-24 CN claimed
WO-2024153235-A1 FUSION PROTEIN OF GE AND GI OF VARICELLA-ZOSTER VIRUS AND USE 厦门大学 2024-07-25 WO claimed
CN-118317791-A Combination therapy using immune cell adapter proteins and immunomodulators 哈普恩治疗公司 2024-07-09 CN claimed
CN-118251414-A Prolonged release immune cell adaptor proteins and methods of treatment 哈普恩治疗公司 2024-06-25 CN claimed
EP-4375367-A1 RECOMBINANT PROTEIN OF NERVE GROWTH FACTOR MUTANT AND USE THEREOF Shanghai Jiao Tong University School of Medicine (CN) 2024-05-29 EP claimed
WO-2023025193-A1 RECOMBINANT PROTEIN OF NERVE GROWTH FACTOR MUTANT AND USE THEREOF 上海交通大学医学院 2023-03-02 WO claimed
WO-2022272033-A2 EXTENDED-RELEASE IMMUNE CELL ENGAGING PROTEINS AND METHODS OF TREATMENT HARPOON THERAPEUTICS, INC. (US) 2022-12-29 WO claimed
WO-2022192225-A1 COMBINATION THERAPY WITH IMMUNE CELL ENGAGING PROTEINS AND IMMUNOMODULATORS HARPOON THERAPEUTICS, INC. (US) 2022-09-15 WO claimed
US-11407818-B2 Antibodies that bind to dengue virus serotype 4 (DENV4) and methods of making and using the same THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-08-09 US claimed
CN-114409802-A Avian influenza virus trimer subunit vaccine and application thereof 中国科学院微生物研究所 2022-04-29 CN claimed
CN-114409803-A Influenza virus trimer subunit vaccine and application thereof 中国科学院微生物研究所 2022-04-29 CN claimed
CN-114349868-A Novel coronavirus S protein receptor binding domain fusion protein containing oligomerization structural domain and application thereof 中国医学科学院基础医学研究所 2022-04-15 CN claimed
CN-114230674-A Novel coronavirus S protein receptor binding domain fusion protein containing Fc structural domain and application thereof 中国医学科学院基础医学研究所 2022-03-25 CN claimed
CN-114196657-A Recombinant limulus three-factor composition and method for detecting endotoxin by using same 厦门鲎试剂生物科技股份有限公司 2022-03-18 CN claimed
CN-112940084-B Serum type4 avian adenovirus subunit vaccine and application thereof 山东省农业科学院家禽研究所(山东省无特定病原鸡研究中心) 2022-02-11 CN claimed