SCHEMBL29366126

SCHEMBL29366126

Fc1cccc(F)c1Cn1c(=S)[nH]c2ccc(Cl)cc21

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PGR P06401 4/20 0.55
PSMB8 P28062 1/20 0.49
APOBEC3G Q9HC16 1/20 0.44
ALDH1A1 P00352 5/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
MPO P05164 1/20 0.40
AGTR1 P30556 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSP90B1 P14625 1/20 0.39
TRAP1 Q12931 1/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495576 0.84 PGR (0.43) PGRAPOBEC3GALDH1A1MEN1KMT2A
SCHEMBL29406168 0.81 APOBEC3G (0.62) PSMB8APOBEC3GALDH1A1MEN1KMT2A
SCHEMBL29533085 0.81 KDM4E (0.53) PGRAPOBEC3GALDH1A1MEN1KMT2A
SCHEMBL29361254 0.75 TRAP1 (0.46) PGRAPOBEC3GALDH1A1MEN1KMT2A
SCHEMBL6540445 0.71 PGR (1.00) PGRAPOBEC3GALDH1A1MEN1KMT2A
SCHEMBL29349517 0.67 TRAP1 (0.43) ALDH1A1MEN1KMT2AMPOTDP1
SCHEMBL5201783 0.67 PDE2A (0.47) ALDH1A1KDM4E
SCHEMBL29360207 0.67 MAPK1 (0.42) PSMB8MEN1KMT2AMPOTDP1
SCHEMBL31395550 0.66 KMT2A (0.53) PGRAPOBEC3GALDH1A1MEN1KMT2A
SCHEMBL29351347 0.65 TDP1 (0.38) APOBEC3GALDH1A1MEN1KMT2AMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260126440-A1 METHODS FOR MEASURING LYMPHOCYTE ACTIVITY KITE PHARMA INC (US) 2026-05-07 US claimed
EP-4680771-A1 IMPACT OF TUMOR MICROENVIRONMENT ON EFFICACY OF IMMUNOTHERAPY Kite Pharma, Inc. (US) 2026-01-21 EP claimed
US-12528856-B2 Chimeric cytokine receptors comprising TGF β binding domains ALLOGENE THERAPEUTICS, INC. (US) 2026-01-20 US claimed
EP-3505623-B1 CELLS FOR IMMUNOTHERAPY ENGINEERED FOR TARGETING ANTIGEN PRESENT BOTH ON IMMUNE CELLS AND PATHOLOGICAL CELLS CELLECTIS (FR) 2025-12-24 EP claimed
US-20250375480-A1 Methods for Generating Engineered Lymphocytes KITE PHARMA INC (US) 2025-12-11 US claimed
US-20250367236-A1 ENGINEERED IMMUNE CELLS UNIKUM THERAPEUTICS APS (DK) 2025-12-04 US claimed
WO-2025245494-A1 TUMOR-TARGETED SPLIT IL12 RECEPTOR AGONISTS REGENERON PHARMACEUTICALS, INC. (US) 2025-11-27 WO claimed
US-20250297219-A1 METHODS FOR GENERATING ENGINEERED LYMPHOCYTES WITH ENRICHED T MEMORY STEM CELLS KITE PHARMA, INC. 2025-09-25 US claimed
US-20250290154-A1 PREDICTIVE MARKERS FOR IMMUNOTHERAPY GILEAD SCIENCES, INC. 2025-09-18 US claimed
EP-4615978-A1 METHODS AND COMPOSITIONS FOR CELL-SURFACE CO-LOCALIZATION OF CHIMERIC PROTEINS Senti Biosciences, Inc. (US) 2025-09-17 EP claimed
US-11454636-B2 Procedure of predicting type 2 diabetes development through analysis of N-glycans attached to the plasma proteins of a healthy person GENOS D.O.O. (HR) 2022-09-27 US claimed
CN-115023444-A Novel IL2 agonists and methods of use thereof 再生元制药公司 2022-09-06 CN claimed
CN-114966011-A Test strip for detecting HIV-1 and HIV-2 antibodies in urine by colloidal gold method 杭州协合医疗用品有限公司 2022-08-30 CN claimed
US-20220265721-A1 TREATMENT USING CHIMERIC RECEPTOR T CELLS INCORPORATING OPTIMIZED POLYFUNCTIONAL T CELLS KITE PHARMA INC (US) 2022-08-25 US claimed
US-11357796-B2 Treatment using chimeric receptor T cells incorporating optimized polyfunctional T cells KITE PHARMA, INC. (US) 2022-06-14 US claimed
US-20220169694-A1 CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY KITE PHARMA, INC. 2022-06-02 US claimed
CN-109725153-B Homogeneous phase immunoassay method and application thereof 科美诊断技术股份有限公司 2022-05-13 CN claimed
CN-114502957-A Kit and method for detecting HIV antibodies 深圳迈瑞生物医疗电子股份有限公司 2022-05-13 CN claimed
WO-2022063201-A1 COMPOUND AND METHOD FOR ENHANCING T-CELL FUNCTION 中国科学院动物研究所 2022-03-31 WO claimed
CN-109477842-B Prediction of the progression of type 2 diabetes by analysis of N-glycoprotein in healthy human plasma proteins 詹诺斯公司 2022-01-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528856-B2 Chimeric cytokine receptors comprising TGF β binding domains IL2RA, IL15RA, LIFR PGR 2006/4885PSMB8 1074/4885APOBEC3G 1356/4885
US-20260126440-A1 METHODS FOR MEASURING LYMPHOCYTE ACTIVITY CD14, CD47, CD4 PGR 1709/4885PSMB8 3572/4885APOBEC3G 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.