SCHEMBL29360287

SCHEMBL29360287

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)C(C)C)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)O

nearest known ligand 0.83

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 8/20 0.71
NPY4R P50391 8/20 0.71
NPY5R Q15761 8/20 0.71
NPY1R P25929 6/20 0.71
CALCR P30988 4/20 0.69
TFPI P10646 3/20 0.64
GLP1R P43220 2/20 0.63
CRHR1 P34998 1/20 0.63
CRHR2 Q13324 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578732 0.94 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31146614 0.94 NPY2R (0.73) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30658322 0.93 NPY2R (0.68) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30578733 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30578734 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30578729 0.93 CALCR (0.73) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495647 0.92 NPY2R (0.77) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30435943 0.92 NPY2R (0.65) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30432747 0.92 CALCR (0.70) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31105560 0.92 NPY2R (0.72) NPY2RNPY4RNPY5RNPY1RCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595314-B2 Antibody specific for GPC3 and methods of use thereof R.P. SCHERER TECHNOLOGIES, LLC (US) 2026-04-07 US disclosed
EP-3915587-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2026-03-25 EP disclosed
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2026-01-01 US disclosed
EP-4647436-A2 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES Sapreme Technologies B.V. (NL) 2025-11-12 EP disclosed
US-12453782-B2 Antibody-oligonucleotide conjugate SAPREME TECHNOLOGIES B.V. (NL) 2025-10-28 US disclosed
EP-3897735-B1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECH BV (NL) 2025-10-22 EP disclosed
US-20250302983-A1 Saponin Conjugates SAPREME TECHNOLOGIES B.V. (NL) 2025-10-02 US disclosed
EP-4619417-A1 NANOCONJUGATES CONTAINING PDGFR-BETA LIGANDS AND USES THEREOF Universitat Autònoma de Barcelona (ES) 2025-09-24 EP disclosed
US-20250243250-A1 THERAPEUTIC NANOCONJUGATES AND USES THEREOF UNIV AUTÒNOMA DE BARCELONA UAB (ES) 2025-07-31 US disclosed
US-20250236679-A1 ANTI-DLL3 ANTIBODY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-24 US disclosed
US-11376326-B2 GPC3-targeting therapeutic agent which is administered to patient for whom the GPC3-targeting therapeutic agent is effective CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-07-05 US disclosed
EP-4015003-A1 IMPROVED ANTIBODY-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2022-06-22 EP disclosed
EP-4010079-A1 IDENTIFICATION AND ELIMINATION OF HCMV-INFECTED CELLS Stichting VU (NL) 2022-06-15 EP disclosed
EP-4007604-A1 ANTIBODY SPECIFIC FOR GPC3 AND METHODS OF USE THEREOF R.P. Scherer Technologies, LLC (US) 2022-06-08 EP disclosed
US-20220153875-A1 ANTIGEN-BINDING MOLECULE CONTAINING ANTIGEN-BINDING DOMAIN OF WHICH BINDING ACTIVITY TO ANTIGEN IS CHANGED DEPENDING ON MTA, AND LIBRARY FOR OBTAINING SAID ANTIGEN-BINDING DOMAIN CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-19 US disclosed
EP-3557260-B1 GPC3-TARGETING DRUG WHICH IS ADMINISTERED TO PATIENT RESPONSIVE TO GPC3-TARGETING DRUG THERAPY CHUGAI PHARMACEUTICAL CO LTD (JP) 2022-05-18 EP disclosed
CN-107964042-B Target tissue specific antigen binding molecules 中外制药株式会社 2022-04-19 CN disclosed
US-20220111066-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECHNOLOGIES B.V. (NL) 2022-04-14 US disclosed
CN-114190218-A Method for constructing rainforest plant community in near-tropical zone 广州普邦园林股份有限公司 2022-03-18 CN disclosed
EP-3943108-A1 ANTIGEN-BINDING MOLECULE CONTAINING ANTIGEN-BINDING DOMAIN OF WHICH BINDING ACTIVITY TO ANTIGEN IS CHANGED DEPENDING ON MTA, AND LIBRARY FOR OBTAINING SAID ANTIGEN-BINDING DOMAIN CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595314-B2 Antibody specific for GPC3 and methods of use thereof IGLV6-57, IGSF11, VSIG8 NPY2R 1177/4885NPY4R 1712/4885NPY5R 2198/4885
US-20250302983-A1 Saponin Conjugates EPCAM, CD47, SHBG NPY2R 3179/4885NPY4R 3993/4885NPY5R 2679/4885
US-20220153875-A1 ANTIGEN-BINDING MOLECULE CONTAINING ANTIGEN-BINDING DOMAIN OF WHICH BINDING ACTIVITY TO ANTIGEN IS CHANGED DEPENDING ON MTA, AND LIBRARY FOR OBTAINING SAID ANTIGEN-BINDING DOMAIN MICA, TNFSF10, HLA-A NPY2R 4829/4885NPY4R 4807/4885NPY5R 4782/4885
US-20260000783-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, FCGR3B NPY2R 3745/4885NPY4R 4102/4885NPY5R 2790/4885
US-20220111066-A1 ANTIBODY-DRUG CONJUGATE WITH IMPROVED THERAPEUTIC WINDOW EPCAM, CD47, EGFR NPY2R 3140/4885NPY4R 3902/4885NPY5R 1884/4885
US-12453782-B2 Antibody-oligonucleotide conjugate CD40, FCGR1A, TNFSF10 NPY2R 2123/4885NPY4R 1770/4885NPY5R 842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.