Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.58 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290633 | 1.00 | ECE1 (0.58) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7290638 | 1.00 | ECE1 (0.58) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8389957 | 0.88 | ADRA1A (0.47) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27765049 | 0.88 | ADRA1A (0.47) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22987357 | 0.87 | ECE1 (0.50) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8388348 | 0.86 | ADRA1A (0.55) | ECE1PLA2G2A | |
| SCHEMBL8390709 | 0.84 | ADRA1A (0.58) | PLA2G2A | |
| SCHEMBL9140084 | 0.84 | USP2 (0.50) | ECE1TERTDPP4DPP8ANPEP | |
| SCHEMBL9140089 | 0.84 | USP2 (0.50) | ECE1TERTDPP4DPP8ANPEP | |
| SCHEMBL7400813 | 0.83 | ECE1 (0.59) | ECE1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085580-A1 | KRAS(G12D) INHIBITORS | WINDERMERE THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| EP-3941527-A1 | METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES | ImmunoGen, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |