Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.58 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360302 | 1.00 | ECE1 (0.58) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7290638 | 1.00 | ECE1 (0.58) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8389957 | 0.88 | ADRA1A (0.47) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27765049 | 0.88 | ADRA1A (0.47) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22987357 | 0.87 | ECE1 (0.50) | ECE1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8388348 | 0.86 | ADRA1A (0.55) | ECE1PLA2G2A | |
| SCHEMBL8390709 | 0.84 | ADRA1A (0.58) | PLA2G2A | |
| SCHEMBL9140084 | 0.84 | USP2 (0.50) | ECE1TERTDPP4DPP8ANPEP | |
| SCHEMBL9140089 | 0.84 | USP2 (0.50) | ECE1TERTDPP4DPP8ANPEP | |
| SCHEMBL7400813 | 0.83 | ECE1 (0.59) | ECE1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803657-A | Pharmaceutical composition | 武汉朗来科技发展有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-114269367-A | Therapeutic peptides | 科巴公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-108883195-A | Prodrugs of cytotoxic active substances with enzymatically cleavable groups | 拜耳制药股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108025086-A | Antibody-active agent conjugates (ADC) of KSP inhibitors and anti-B7H 3 antibodies | 拜耳制药股份公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-108025084-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107921146-A | Spindle drives the antibody drug conjugate (ADC) of albumen (KSP) inhibitor and the antibody of anti-CD123 | 拜耳医药股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107921145-A | The antibody drug conjugate of KSP inhibitor and anti-TWEAKR antibody（ADC） | 拜耳医药股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| EP-2882764-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | Roche Diagnostics GmbH (DE) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014019708-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ROCHE DIAGNOSTICS GMBH (DE) | 2014-02-06 | — | — | WO | disclosed |
| CN-101868563-B | Base processing agent for metal material and method for processing base for metal material | NIHON PARKERIZING | 2012-09-12 | — | — | CN | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| EP-0626942-B1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | BLACK JAMES FOUNDATION (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5514683-A | LIGANDS FKOR CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0626942-A1 | BICYCLO 2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS. | BLACK JAMES FOUNDATION (GB) | 1994-12-07 | — | — | EP | disclosed |
| EP-0546108-A4 | PRO-DRUGS FOR CCK ANTAGONISTS | — | 1993-09-22 | — | — | EP | disclosed |
| WO-1993016982-A1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |
| EP-0546108-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| US-4963539-A | TREATING HEART FAILURE, PAIN OR DIARRHEA | E. R. SQUIBB & SONS, INC. (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0306879-A2 | Phosphonate and phosphonamide endopeptidase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1989-03-15 | — | — | EP | disclosed |