SCHEMBL172476

SCHEMBL172476

COC(=O)c1ccc(O)c(C)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.71
CA2 P00918 6/20 0.71
CA12 O43570 5/20 0.71
CA7 P43166 5/20 0.71
CA9 Q16790 5/20 0.71
CA14 Q9ULX7 5/20 0.71
XDH P47989 2/20 0.71
ALDH1A1 P00352 4/20 0.62
MAPT P10636 4/20 0.62
KDM4E B2RXH2 3/20 0.62
LMNA P02545 3/20 0.62
HPGD P15428 3/20 0.62
HSD17B10 Q99714 3/20 0.62
TP53 P04637 2/20 0.62
ALOX15 P16050 2/20 0.62
ALOX12 P18054 2/20 0.62
MEN1 O00255 1/20 0.62
HTT P42858 1/20 0.62
KMT2A Q03164 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10421921 0.89 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL10420353 0.88 CA12 (0.57) CA1CA2CA12CA7CA9
SCHEMBL10420343 0.87 CA12 (0.56) CA1CA2CA12CA7CA9
SCHEMBL31156266 0.87 CA1 (0.65) CA1CA2CA12CA7CA9
SCHEMBL498118 0.85 ERN1 (0.65) CA1CA2CA12CA7CA9
SCHEMBL197972 0.84 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL30809635 0.84 CA1 (0.71) CA1CA2CA12CA7CA9
Methyl Protocatechuate SCHEMBL38624 0.83 CA1 (1.00) CA1CA2CA12CA7CA9
Methyl Protocatechuate SCHEMBL29360855 0.83 CA1 (1.00) CA1CA2CA12CA7CA9
SCHEMBL30029511 0.83 MAPT (0.63) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN claimed
CN-110093064-B Preparation method and application of long-afterglow luminescent ink 重庆理工大学 2021-07-13 CN claimed
US-20260138990-A1 TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
EP-4702026-A1 TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF Aeovian Pharmaceuticals, Inc. (US) 2026-03-04 EP disclosed
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4633683-A1 CYCLOOCTENE COMPOSITIONS AND USES THEREOF Biogen MA Inc. (US) 2025-10-22 EP disclosed
US-12421452-B2 Method for producing liquid-crystal polyester processed product HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2025-09-23 US disclosed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. 2025-05-22 US disclosed
CN-119546566-A FTO inhibitors 瑞璞鑫(苏州)生物科技有限公司 2025-02-28 CN disclosed
US-4939267-A Viricides STERLING DRUG INC. (US) 1990-07-03 US disclosed
US-4937281-A ACRYLIC BINDER OF ALKYL ACRYLATES HAVING PENDANT AMINOESTERS OR HYDROXYAMINO ESTER GROUPS, SOLVENT AND AN ALKYL P-HYDROXY BENZOATE AS CURING CATALYST; AUTO REFINISHES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-26 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
US-4895768-A CROSSLINKED ACRYLIC ESTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-23 US disclosed
US-4843087-A OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES STERLING DRUG INC. (US) 1989-06-27 US disclosed
EP-0137242-A2 (Substituted) Phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof STERLING WINTHROP INC. (US) 1985-04-17 EP disclosed
US-4138579-A INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1979-02-06 US disclosed
US-4051319-A INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1977-09-27 US disclosed
US-3957833-A KILLING INSECTS, HORMONES HOFFMANN-LA ROCHE INC. (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138990-A1 TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF CD38, BCL9, BCL6B CA1 789/4885CA2 187/4885CA12 75/4885
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 CA1 3210/4885CA2 3929/4885CA12 4386/4885
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC CA1 4855/4885CA2 4707/4885CA12 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.