Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102707 | 0.98 | HCAR2 (0.49) | HCAR2ATMTHRB | |
| SCHEMBL7102709 | 0.98 | HCAR2 (0.49) | HCAR2ATMTHRB | |
| SCHEMBL10457601 | 0.93 | ATM (0.38) | HCAR2ATMTHRB | |
| SCHEMBL10457602 | 0.93 | ATM (0.38) | HCAR2ATMTHRB | |
| SCHEMBL2522481 | 0.93 | ATM (0.38) | HCAR2ATMTHRB | |
| SCHEMBL1426647 | 0.93 | ATM (0.38) | HCAR2ATMTHRB | |
| SCHEMBL11644944 | 0.93 | ATM (0.38) | HCAR2ATMTHRB | |
| SCHEMBL3735408 | 0.93 | ATM (0.38) | HCAR2ATMTHRB | |
| SCHEMBL10456292 | 0.92 | ATM (0.39) | HCAR2ATMTHRB | |
| SCHEMBL1426811 | 0.92 | ATM (0.39) | HCAR2ATMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022016202-A1 | PLEUROMUTILIN DERIVATIVE AND/OR IVERMECTIN, FOR THERAPY OF INFECTIONS, IN PARTICULAR CORONA VIRUSES | ASCHER GERD (AT) | 2022-01-27 | — | — | WO | claimed |
| US-20230021520-A1 | 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT | H. LUNDBECK A/S (DK) | 2023-01-26 | — | — | US | disclosed |
| CN-115340538-A | 8-phenyliminomethyl berberine type derivatives and application thereof in preparing medicines | 中国医学科学院药物研究所 | 2022-11-15 | — | — | CN | disclosed |
| US-11458134-B2 | 1-[2-(2,4-dimeihylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment | H. LUNDBECK A/S (DK) | 2022-10-04 | — | — | US | disclosed |
| CN-110840847-B | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11458134-B2 | 1-[2-(2,4-dimeihylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment | HTR3A, HTR2C, HTR2A | HCAR2 489/4885ATM 3801/4885THRB 1371/4885 |
| US-20230021520-A1 | 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT | HTR3A, HTR2C, HTR5A | HCAR2 710/4885ATM 3318/4885THRB 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.