SCHEMBL29362454

SCHEMBL29362454

Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.75
▸ TERT O14746 2/20 0.64
▸ POLB P06746 2/20 0.57
▸ ENPP1 P22413 2/20 0.54
▸ P2RY1 P47900 1/20 0.54
▸ F2 P00734 1/20 0.53
▸ TK1 P04183 1/20 0.52
▸ TYMS P04818 1/20 0.52
▸ RNASEL Q05823 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29607650 1.00 DTYMK (0.75) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL29769834 1.00 DTYMK (0.75) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL30122220 1.00 DTYMK (0.75) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL17268344 0.95 DTYMK (0.74) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL8613042 0.95 DTYMK (0.74) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL8612856 0.95 DTYMK (0.74) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL16983788 0.93 DTYMK (0.66) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL30632043 0.93 DTYMK (0.66) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL16979766 0.93 DTYMK (0.66) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL9160842 0.93 DTYMK (0.83) DTYMKTERTPOLBENPP1P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629415-B2 Vaccine adjuvants THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2026-05-19 — — US claimed
US-20260108454-A1 Innate Targeting of Adoptive Cellular Therapies QU BIOLOGICS INC (CA) 2026-04-23 — — US claimed
US-12594291-B2 Intratumoral alpha-emitter radiation and activation of cytoplasmatic sensors for intracellular pathogen ALPHA TAU MEDICAL LTD (IL) 2026-04-07 — — US claimed
EP-4692372-A1 UNIVERSAL LANDING PLATFORM UNIVERCELLS FRANCE SAS (FR) 2026-02-11 — — EP claimed
EP-3873598-B1 INTRATUMORAL ALPHA-EMITTER RADIATION AND ACTIVATION OF CYTOPLASMATIC SENSORS FOR INTRACELLULAR PATHOGEN ALPHA TAU MEDICAL LTD (IL) 2025-07-02 — — EP claimed
US-20250186486-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION BAYLOR COLLEGE OF MEDICINE (US) 2025-06-12 — — US claimed
CN-120118149-A Polypeptide for inhibiting TBK1 and inflammation and application thereof 中国科学院武汉病毒研究所 2025-06-10 — — CN claimed
EP-4559479-A2 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-05-28 — — EP claimed
EP-4493166-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION Baylor College of Medicine (US) 2025-01-22 — — EP claimed
CN-119278032-A Enhancement of persistent antitumor immunity by multifactorial immunomodulation 贝勒医学院 2025-01-07 — — CN claimed
US-20230093460-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS YALE UNIVERSITY (US) 2023-03-23 — — US claimed
US-20230079745-A1 COMPOSITIONS COMPRISING BACTERIALLY DERIVED MINICELLS AND METHODS OF USING THE SAME ENGENEIC MOLECULAR DELIVERY PTY LTD (AU) 2023-03-16 — — US claimed
WO-2023034864-A1 COMPOSITIONS AND METHODS FOR TREATING CANCERS YALE UNIVERSITY (US) 2023-03-09 — — WO claimed
CN-115611988-A Compounds for targeted immunotherapy 博笛生物科技有限公司 2023-01-17 — — CN claimed
WO-2023278897-A1 COMPOSITIONS AND METHODS FOR TREATING CANCERS YALE UNIVERSITY (US) 2023-01-05 — — WO claimed
EP-4097473-A1 METHODS FOR ASSIGNING A PHENOTYPIC SIGNATURE FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DE) 2022-12-07 — — EP claimed
WO-2022215079-A1 NANOVACCINES FOR TREATMENT OF VIRAL DISEASES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-10-13 — — WO claimed
WO-2022047424-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS YALE UNIVERSITY (US) 2022-03-03 — — WO claimed
CN-114081961-A Composite nano-particles, preparation method and application 中国科学技术大学 2022-02-25 — — CN claimed
WO-2022032043-A1 DENDRITIC CELL ACTIVATING THERAPY AS AN ADJUNCT TO RADIATION THERAPY MONTEFIORE MEDICAL CENTER (US) 2022-02-10 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108454-A1 Innate Targeting of Adoptive Cellular Therapies MYD88, TLR3, TLR9 DTYMK 777/4885TERT 3595/4885POLB 2781/4885
US-12629415-B2 Vaccine adjuvants STING1, TLR9, TLR3 DTYMK 207/4885TERT 1293/4885POLB 563/4885
US-12594291-B2 Intratumoral alpha-emitter radiation and activation of cytoplasmatic sensors for intracellular pathogen STING1, IFNAR1, IFNG DTYMK 1783/4885TERT 4566/4885POLB 3260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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