SCHEMBL29607650

SCHEMBL29607650

Cc1cn(C2CC(OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)CC3O)C(COP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.75
▸ TERT O14746 2/20 0.64
▸ POLB P06746 2/20 0.57
▸ ENPP1 P22413 2/20 0.54
▸ P2RY1 P47900 1/20 0.54
▸ F2 P00734 1/20 0.53
▸ TK1 P04183 1/20 0.52
▸ TYMS P04818 1/20 0.52
▸ RNASEL Q05823 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29769834 1.00 DTYMK (0.75) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL30122220 1.00 DTYMK (0.75) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL29362454 1.00 DTYMK (0.75) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL17268344 0.95 DTYMK (0.74) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL8613042 0.95 DTYMK (0.74) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL8612856 0.95 DTYMK (0.74) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL16983788 0.93 DTYMK (0.66) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL30632043 0.93 DTYMK (0.66) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL16979766 0.93 DTYMK (0.66) DTYMKTERTPOLBENPP1P2RY1
SCHEMBL9160842 0.93 DTYMK (0.83) DTYMKTERTPOLBENPP1P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4377456-A2 GENE EDITING SYSTEMS COMPRISING A NUCLEASE AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2024-06-05 — — EP claimed
US-20230059141-A1 GENE EDITING SYSTEMS COMPRISING A NUCLEASE AND USES THEREOF Arbor Biotechnologies, Inc. 2023-02-23 — — US claimed
WO-2023010084-A2 GENE EDITING SYSTEMS COMPRISING A NUCLEASE AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2023-02-02 — — WO claimed
EP-4735603-A2 GUIDE RNA COMPOSITIONS nChroma Bio, Inc. (US) 2026-05-06 — — EP disclosed
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER APTAH BIO INC (US) 2026-03-26 — — US disclosed
EP-4692338-A1 CAS12 PROTEIN AND USE THEREOF Guangzhou Reforgene Medicine Co., Ltd. (CN) 2026-02-11 — — EP disclosed
US-20260022377-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES APTAH BIO INC (US) 2026-01-22 — — US disclosed
US-20260009052-A1 CAS12 PROTEINS AND USES THEREOF GUANGZHOU REFORGENE MEDICINE CO., LTD. (CN) 2026-01-08 — — US disclosed
US-20250388597-A1 BIFUNCTIONAL PHOTOCROSSLINKING PROBES FOR COVALENT CAPTURE OF PROTEIN-NUCLEIC ACID COMPLEXES IN CELLS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-12-25 — — US disclosed
US-20250369048-A1 LABELING OF NUCLEIC ACID MOLECULE BY INTERSTRAND CROSSLINKED DOUBLE-STRAND DNA HITACHI, LTD. (JP) 2025-12-04 — — US disclosed
EP-4652277-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
WO-2023010084-A2 GENE EDITING SYSTEMS COMPRISING A NUCLEASE AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2023-02-02 — — WO disclosed
WO-2023288111-A2 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR GENE EXPRESSION REGULATION APTAH BIO, INC. (US) 2023-01-19 — — WO disclosed
WO-2022265032-A1 LABELING OF NUCLEIC ACID MOLECULE BY INTERSTRAND CROSSLINKED DOUBLE-STRAND DNA 株式会社日立製作所 2022-12-22 — — WO disclosed
US-20220396812-A1 RNA-GUIDED NUCLEIC ACID MODIFYING ENZYMES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-12-15 — — US disclosed
US-20220348985-A1 FORCED INTERCALATION (FIT)-APTAMERS: PROBES BASED ON FORCED INTERCALATION NORTHWESTERN UNIVERSITY 2022-11-03 — — US disclosed
EP-4039690-A1 A SUBSTANTIALLY DIASTEREOMERICALLY PURE PHOSPHORAMIDOCHLORIDATE, A METHOD AND A PHARMACEUTICAL COMPOSITION Eisai R&D Management Co., Ltd. (JP) 2022-08-10 — — EP disclosed
WO-2022140577-A2 COMPOSITIONS AND METHODS FOR EPIGENETIC EDITING CHROMA MEDICINE, INC. (US) 2022-06-30 — — WO disclosed
US-11371062-B2 RNA-guided nucleic acid modifying enzymes and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-06-28 — — US disclosed
WO-2022104381-A1 A MINIMAL CRISPRi/a SYSTEM FOR TARGETED GENOME REGULATION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER RPRD2, RTCB, UPF1 DTYMK 204/4885TERT 723/4885POLB 224/4885
US-20260022377-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES PRNP, UPF1, FUS DTYMK 533/4885TERT 397/4885POLB 387/4885
US-20250388597-A1 BIFUNCTIONAL PHOTOCROSSLINKING PROBES FOR COVALENT CAPTURE OF PROTEIN-NUCLEIC ACID COMPLEXES IN CELLS PCNA, DDB1, DCLRE1A DTYMK 573/4885TERT 2525/4885POLB 101/4885
US-20260009052-A1 CAS12 PROTEINS AND USES THEREOF RBM12, STING1, TTLL12 DTYMK 644/4885TERT 3318/4885POLB 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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