Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933192 | 0.78 | KMT2A (0.43) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL2936428 | 0.76 | AR (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL13178015 | 0.76 | KMT2A (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL30317956 | 0.74 | NPC1 (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL16578878 | 0.74 | ALDH1A1 (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL18338361 | 0.73 | LMNA (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL30587612 | 0.73 | CACNA1G (0.55) | LMNAALDH1A1HPGDSMN1; SMN2CACNA1G | |
| SCHEMBL18366115 | 0.73 | CACNA1G (0.55) | LMNAALDH1A1HPGDSMN1; SMN2CACNA1G | |
| SCHEMBL2935227 | 0.73 | ALDH1A1 (0.44) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL28698821 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091950-B1 | OXADIAZOLE DERIVATIVES AS S1P1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2010-09-22 | — | — | EP | disclosed |