SCHEMBL29363

SCHEMBL29363

Cn1cccc1C(=O)N1CCN(C(=O)Nc2ccc(N3CCC(C(=O)N4CCOCC4)CC3)cc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 20/20 1.00
CRBN Q96SW2 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27787 0.92 HPGDS (1.00) HPGDSCRBN
SCHEMBL27589 0.91 HPGDS (1.00) HPGDSCRBN
SCHEMBL23000070 0.90 HPGDS (0.81) HPGDSCRBN
SCHEMBL28492 0.87 HPGDS (0.81) HPGDSCRBN
SCHEMBL28315 0.86 HPGDS (1.00) HPGDSCRBN
SCHEMBL28755 0.85 HPGDS (1.00) HPGDS
SCHEMBL9998846 0.85 HPGDS (1.00) HPGDSCRBN
SCHEMBL27841 0.85 HPGDS (1.00) HPGDSCRBN
SCHEMBL28314 0.84 HPGDS (0.73) HPGDSCRBN
SCHEMBL23017395 0.81 HPGDS (0.73) HPGDSCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4482481-B1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH S A (ES) 2025-11-12 EP claimed
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES REGENTS OF THE UNIVERSITY OF MINNESOTA 2025-05-15 US claimed
EP-4482481-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES Som Innovation Biotech, S.L. (ES) 2025-01-01 EP claimed
EP-3782648-B1 PROSTAGLANDIN D2 PRODUCTION INHIBITORS AS PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA NATIONAL UNIV CORPORATION TOKYO UNIV OF AGRICULTURE AND TECHNOLOGY (JP) 2024-09-18 EP claimed
US-11883410-B2 Preventative and therapeutic agents for sarcopenia NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLGY (JP) 2024-01-30 US claimed
WO-2023156645-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH, S.A. (ES) 2023-08-24 WO claimed
EP-4230196-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES Som Innovation Biotech, S.A. (ES) 2023-08-23 EP claimed
US-20210161908-A1 PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) 2021-06-03 US claimed
EP-3782648-A1 PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA National University Corporation Tokyo University of Agriculture and Technology (JP) 2021-02-24 EP claimed
EP-4482481-B1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH S A (ES) 2025-11-12 EP disclosed
WO-2025104229-A1 HEMATOPOIETIC PROSTAGLANDIN SYNTHASE (HPGDS) INHIBITION FOR TREATING CANCER VIB VZW (BE) 2025-05-22 WO disclosed
WO-2025104238-A1 INHIBITION OF PROSTAGLANDIN D2 RECEPTOR 2 AS MEANS FOR TREATING CANCER VIB VZW (BE) 2025-05-22 WO disclosed
WO-2025104233-A1 INHIBITION OF PROSTAGLANDIN D2 RECEPTOR 1 AS MEANS FOR TREATING CANCER VIB VZW (BE) 2025-05-22 WO disclosed
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES REGENTS OF THE UNIVERSITY OF MINNESOTA 2025-05-15 US disclosed
US-20210161908-A1 PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) 2021-06-03 US disclosed
WO-2021066136-A1 THERAPEUTIC AGENT FOR MUSCULAR DYSTROPHY 国立大学法人東京大学 2021-04-08 WO disclosed
EP-3782648-A1 PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA National University Corporation Tokyo University of Agriculture and Technology (JP) 2021-02-24 EP disclosed
WO-2019203296-A1 PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA 国立大学法人東京農工大学 2019-10-24 WO disclosed
EP-3351542-A1 NEW CRYSTAL OF PIPERAZINE COMPOUND Taiho Pharmaceutical Co., Ltd. (JP) 2018-07-25 EP disclosed
EP-2407466-A1 PIPERAZINE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHASE Taiho Pharmaceutical Co., Ltd. (JP) 2012-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES MTPN, UTRN, TTN HPGDS 4772/4885CRBN 313/4885
US-11883410-B2 Preventative and therapeutic agents for sarcopenia CPT1B, TNNC1, MTPN HPGDS 32/4885CRBN 3896/4885
US-20210161908-A1 PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA CPT1B, TNNC1, MTPN HPGDS 32/4885CRBN 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.