Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 4/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCND3 | P30281 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029012 | 1.00 | ITK (0.43) | ITKSLC2A1FGFR1CDK4CCNA2 | |
| SCHEMBL29364422 | 0.90 | SLC2A1 (0.41) | ITKSLC2A1CDK2KDM4ERAB9A | |
| SCHEMBL25029246 | 0.90 | SLC2A1 (0.41) | ITKSLC2A1CDK2KDM4ERAB9A | |
| SCHEMBL2189184 | 0.79 | FGFR1 (0.55) | ITKFGFR1KDM4ERAB9AFLT1 | |
| SCHEMBL29363709 | 0.79 | FGFR1 (0.55) | ITKFGFR1KDM4ERAB9AFLT1 | |
| SCHEMBL7004636 | 0.74 | RAB9A (0.51) | SLC2A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL25029256 | 0.72 | MAPT (0.60) | ITKFGFR1KDM4ERAB9AMAPT | |
| SCHEMBL7004495 | 0.70 | AR (0.50) | SLC2A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL62397 | 0.70 | RAB9A (0.61) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL17179394 | 0.69 | AR (0.62) | KDM4ERAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |