SCHEMBL7004495

SCHEMBL7004495

Cc1ccc(N(C)C)cc1-c1ccc2ccccc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.50
SLC2A1 P11166 1/20 0.46
NCF1 P14598 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
RAB9A P51151 2/20 0.44
PSMB5 P28074 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CNR2 P34972 1/20 0.43
TERT O14746 1/20 0.43
APP P05067 1/20 0.43
NPC1 O15118 2/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HCRTR1 O43613 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004513 0.84 AR (0.50) ARMEN1KMT2ARAB9AKDM4E
SCHEMBL7004428 0.81 AR (0.47) ARMEN1KMT2ARAB9AKDM4E
SCHEMBL12319823 0.81 AR (0.57) ARMEN1KMT2ARAB9AKDM4E
SCHEMBL7004760 0.79 NCF1 (0.42) ARSLC2A1NCF1MEN1KMT2A
SCHEMBL15683332 0.78 MEN1 (0.56) ARNCF1MEN1KMT2ARAB9A
SCHEMBL12447362 0.78 AR (0.59) ARMEN1KMT2ARAB9AKDM4E
SCHEMBL4788772 0.77 AR (0.64) ARNCF1MEN1KMT2ARAB9A
SCHEMBL29986262 0.77 AR (0.64) ARNCF1MEN1KMT2ARAB9A
SCHEMBL7005634 0.76 SMN1; SMN2 (0.60) ARMEN1KMT2ARAB9AKDM4E
SCHEMBL62397 0.76 RAB9A (0.61) ARNCF1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012064499-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2012-05-18 WO disclosed