SCHEMBL29363938

SCHEMBL29363938

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.78
▸ OPRM1 P35372 2/20 0.64
▸ OPRD1 P41143 1/20 0.62
▸ OPRK1 P41145 1/20 0.62
▸ REN P00797 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531036 0.90 SLC6A2 (0.75) SLC6A2OPRM1OPRD1REN
SCHEMBL29530910 0.90 SLC6A2 (0.75) SLC6A2OPRM1OPRD1REN
SCHEMBL29576785 0.90 SLC6A2 (0.74) SLC6A2OPRM1OPRD1OPRK1
SCHEMBL29471736 0.88 SLC6A2 (0.63) SLC6A2OPRM1OPRD1
SCHEMBL29353395 0.88 SLC6A2 (0.77) SLC6A2OPRM1OPRD1OPRK1
SCHEMBL30423227 0.88 OPRM1 (0.74) SLC6A2OPRM1OPRD1
SCHEMBL29571797 0.88 OPRM1 (0.74) SLC6A2OPRM1OPRD1
Endomorphin 2 SCHEMBL13252092 0.87 OPRM1 (0.76) OPRM1OPRD1OPRK1
Endomorphin 2 SCHEMBL22649436 0.87 OPRM1 (0.76) OPRM1OPRD1OPRK1
Endomorphin 2 SCHEMBL29577635 0.87 OPRM1 (0.76) OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084021-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR HIDRADENITIS SUPPURATIVA ANAPTYSBIO, INC. 2024-03-14 — — US claimed
US-20230272092-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS ANAPTYSBIO, INC. 2023-08-31 — — US claimed
CN-116406295-A Anti-interleukin 36 receptor (IL-36R) therapy against ichthyosis 安奈普泰斯生物有限公司 2023-07-07 — — CN claimed
EP-4188441-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS AnaptysBio, Inc. (US) 2023-06-07 — — EP claimed
CN-115925932-A Antibodies against interleukin 36 receptor (IL-36R) 安奈普泰斯生物有限公司 2023-04-07 — — CN claimed
WO-2022150644-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ACNE ANAPTYSBIO, INC. (US) 2022-07-14 — — WO claimed
WO-2022150642-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR HIDRADENITIS SUPPURATIVA ANAPTYSBIO, INC. (US) 2022-07-14 — — WO claimed
WO-2022026832-A9 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS ANAPTYSBIO, INC. (US) 2022-03-24 — — WO claimed
WO-2022026832-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS ANAPTYSBIO, INC. (US) 2022-02-03 — — WO claimed
WO-2022026829-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR SKIN TOXICITY ANAPTYSBIO, INC. (US) 2022-02-03 — — WO claimed
CN-117285644-B Phase change regulating element and application thereof 清华大学 2026-05-15 — — CN disclosed
CN-116583298-B PD-1 targeted IL-15/IL-15RαFC fusion proteins with improved properties 基因泰克公司 2026-05-12 — — CN disclosed
US-20260097063-A1 ANTI-C5 ANTIBODY/C5 IRNA DOSING REGIMENS FOR TREATING C5-ASSOCIATED DISEASES REGENERON PHARMA (US) 2026-04-09 — — US disclosed
US-20260022181-A1 ANTIBODIES DIRECTED AGAINST INTERLEUKIN 36 RECEPTOR (IL-36R) ANAPTYSBIO INC (US) 2026-01-22 — — US disclosed
US-12421300-B2 Preparation method and application of single-chain antibody fragment targeting SARS-CoV-2 nucleocapsid protein NANJING UNIVERSITY (CN) 2025-09-23 — — US disclosed
CN-114044825-A anti-Siglec-8 antibodies and methods of use thereof 爱乐科斯公司 2022-02-15 — — CN disclosed
WO-2022026832-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS ANAPTYSBIO, INC. (US) 2022-02-03 — — WO disclosed
WO-2022026829-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR SKIN TOXICITY ANAPTYSBIO, INC. (US) 2022-02-03 — — WO disclosed
CN-107074948-B Antibodies that bind AXL 根马布股份公司 2022-01-28 — — CN disclosed
CN-113980128-A Anti-human glycocholic acid monoclonal antibody and application thereof 中元汇吉生物技术股份有限公司 2022-01-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097063-A1 ANTI-C5 ANTIBODY/C5 IRNA DOSING REGIMENS FOR TREATING C5-ASSOCIATED DISEASES LDLR, CHRNG, FCGR2A SLC6A2 2979/4885OPRM1 1870/4885OPRD1 2802/4885
US-20260022181-A1 ANTIBODIES DIRECTED AGAINST INTERLEUKIN 36 RECEPTOR (IL-36R) IL36G, IGLV6-57, IL23R SLC6A2 3212/4885OPRM1 2227/4885OPRD1 2855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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