SCHEMBL29471736

SCHEMBL29471736

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.63
▸ DPP3 Q9NY33 5/20 0.61
▸ OPRM1 P35372 2/20 0.57
▸ OPRD1 P41143 2/20 0.57
▸ CAPN1 P07384 1/20 0.57
▸ CTSB P07858 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350618 1.00 SLC6A2 (0.63) SLC6A2DPP3OPRM1OPRD1CAPN1
SCHEMBL30392261 0.90 DPP3 (0.61) SLC6A2DPP3OPRM1CAPN1CTSB
SCHEMBL29772686 0.90 DPP3 (0.65) SLC6A2DPP3OPRM1
SCHEMBL29577213 0.90 DPP3 (0.65) SLC6A2DPP3OPRM1
SCHEMBL30659496 0.90 DPP3 (0.64) DPP3OPRM1OPRD1
SCHEMBL29683171 0.90 KISS1R (0.62) SLC6A2OPRM1CAPN1CTSB
Spinorphin SCHEMBL25273730 0.89 KISS1R (0.60) SLC6A2DPP3OPRM1CAPN1CTSB
Spinorphin SCHEMBL25217672 0.89 KISS1R (0.60) SLC6A2DPP3OPRM1CAPN1CTSB
SCHEMBL29363938 0.88 SLC6A2 (0.78) SLC6A2OPRM1OPRD1
Endomorphin-1 SCHEMBL21811384 0.88 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3921420-B1 DRUG DELIVERY COMPOSITIONS FOR OCULAR ADMINISTRATION OF THERAPEUTICS AND METHODS OF USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-04-08 — — EP disclosed
US-20260053737-A1 METHODS AND COMPOSITIONS FOR SUSTAINED RELEASE MICROPARTICLES FOR OCULAR DRUG DELIVERY OHIO STATE INNOVATION FOUNDATION (US) 2026-02-26 — — US disclosed
US-20260007778-A1 METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES TRANSLATUM MEDICUS INC (CA) 2026-01-08 — — US disclosed
US-20250387449-A1 PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER ALBIREO AB (SE) 2025-12-25 — — US disclosed
EP-4662203-A1 BINDARIT CONJUGATES, COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES OR DISORDERS Translatum Medicus Inc. (CA) 2025-12-17 — — EP disclosed
EP-3956813-B1 DETECTION, PREDICTION, AND CLASSIFICATION FOR OCULAR DISEASE TRACERY OPHTHALMICS INC (CA) 2025-11-26 — — EP disclosed
US-12377171-B2 Methods for treating and diagnosing blinding eye diseases Translatum Medicus Inc. (CA) 2025-08-05 — — US disclosed
US-12357564-B2 Methods and compositions for sustained release microparticles for ocular drug delivery OHIO STATE INNOVATION FOUNDATION (US) 2025-07-15 — — US disclosed
US-20250152781-A1 TISSUE ENGINEERING AND DRUG DELIVERY DEVICE OHIO STATE INNOVATION FOUNDATION 2025-05-15 — — US disclosed
US-20240404619-A1 Machine Learning and Molecular Simulation Based Methods for Enhancing Binding and Activity Prediction THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-12-05 — — US disclosed
WO-2023133560-A2 TISSUE ENGINEERING AND DRUG DELIVERY DEVICE OHIO STATE INNOVATION FOUNDATION (US) 2023-07-13 — — WO disclosed
US-11660266-B2 Methods and compositions for sustained release microparticles for ocular drug delivery OHIO STATE INNOVATION FOUNDATION (US) 2023-05-30 — — US disclosed
WO-2022271255-A1 TISSUE-ENGINEERED SCAFFOLDS AND METHODS OF MAKING GEORGIA TECH RESEARCH CORPORATION (US) 2022-12-29 — — WO disclosed
US-11529340-B2 Combination for treating pain REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-12-20 — — US disclosed
US-20220226446-A1 NEUROTOXIN COMPOSITIONS FOR USE IN IMPROVING LUNG FUNCTION BONTI INC (US) 2022-07-21 — — US disclosed
US-11383084-B2 Treatment of dermatological conditions via neuromodulation PALO ALTO INVESTORS (US) 2022-07-12 — — US disclosed
US-20220207729-A1 DETECTION, PREDICTION, AND CLASSIFICATION FOR OCULAR DISEASE TRACERY OPHTHALMICS INC. (CA) 2022-06-30 — — US disclosed
US-20220117888-A1 DRUG DELIVERY COMPOSITIONS FOR OCULAR ADMINISTRATION OF THERAPEUTICS AND METHODS OF USE THEREOF OHIO STATE INNOVATION FOUNDATION 2022-04-21 — — US disclosed
US-20220118159-A1 ANTIOXIDANT-RELEASING VITREOUS SUBSTITUTES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION 2022-04-21 — — US disclosed
EP-3956813-A1 DETECTION, PREDICTION, AND CLASSIFICATION FOR OCULAR DISEASE Boyd, Shelley (CA) 2022-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053737-A1 METHODS AND COMPOSITIONS FOR SUSTAINED RELEASE MICROPARTICLES FOR OCULAR DRUG DELIVERY ARG1, ARG2, PDE6D SLC6A2 1265/4885DPP3 1259/4885OPRM1 681/4885
US-11660266-B2 Methods and compositions for sustained release microparticles for ocular drug delivery PDE6C, CHMP4B, PDE6D SLC6A2 221/4885DPP3 1091/4885OPRM1 1800/4885
US-20260007778-A1 METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES AGER, ALDH1A2, RBP1 SLC6A2 174/4885DPP3 1130/4885OPRM1 1700/4885
US-12357564-B2 Methods and compositions for sustained release microparticles for ocular drug delivery PDE6C, CHMP4B, PDE6D SLC6A2 221/4885DPP3 1091/4885OPRM1 1800/4885
US-20250387449-A1 PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER SLC10A2, SLC10A1, ABCB11 SLC6A2 60/4885DPP3 896/4885OPRM1 1363/4885
US-12377171-B2 Methods for treating and diagnosing blinding eye diseases ALDH1A2, RBP1, RBP4 SLC6A2 2985/4885DPP3 584/4885OPRM1 4602/4885
US-11529340-B2 Combination for treating pain OPRL1, ACHE, OPRK1 SLC6A2 644/4885DPP3 1145/4885OPRM1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback