Purine

Purine

SCHEMBL712798

N.c1ncc2[nH]cnc2n1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
PI4KA P42356 2/20 0.38
PI4K2B Q8TCG2 2/20 0.38
PI4K2A Q9BTU6 2/20 0.38
PI4KB Q9UBF8 2/20 0.38
LRRK2 Q5S007 2/20 0.38
LMNA P02545 2/20 0.38
DRD3 P35462 1/20 0.38
XDH P47989 1/20 0.38
G6PD P11413 1/20 0.36
CDK2 P24941 3/20 0.36
RXFP1 Q9HBX9 1/20 0.36
METAP2 P50579 1/20 0.35
METAP1 P53582 1/20 0.35
PDPK1 O15530 2/20 0.34
TP53 P04637 2/20 0.34
CHEK1 O14757 1/20 0.34
AURKA O14965 1/20 0.34
CHEK2 O96017 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purine SCHEMBL27516942 0.98 ALDH1A1 (0.44) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL29703771 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL6421380 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL29365913 0.98
Purine SCHEMBL30862524 0.98
Purine SCHEMBL2120554 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL6438164 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL7787140 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL31628309 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL619820 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110099682-A Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof 杭州多禧生物科技有限公司 2019-08-06 CN claimed
CN-107665777-A A kind of preparation method of biomass-based active carbon electrode material 北京化工大学 2018-02-06 CN claimed
CN-106604733-A Adjunctive therapy with 25-hydroxyvitamin D 欧普科爱尔兰环球控股有限公司 2017-04-26 CN claimed
CN-104053648-B Piperazinyl derivatives for the treatment of cancer M-H·皮蒂 2016-09-28 CN claimed
CN-103468950-B Method for removing metal ion purity of rare earth aqueous solution extraction INST PROCESS ENG CAS 2015-05-20 CN claimed
CN-104053648-A Piperazinyl derivatives for the treatment of cancer PITTY MARC HENRY 2014-09-17 CN claimed
CN-103468950-A Method for removing metal ion purity of rare earth aqueous solution extraction INST PROCESS ENG CAS 2013-12-25 CN claimed
CN-103461124-A Tissue culture and rapid propagation process for seedless golden silk jujube DEZHOU COUNTY AGRICULTURAL SCIENCE RES INST 2013-12-25 CN claimed
CN-1116238-A Method for cultiating tomato with function of anti virus of mosaic of cucumber by gene engineering UNIV BEIJING (CN) 1996-02-07 CN claimed
WO-2025073885-A1 COMPOSITION FOR USE IN PATIENTS WITH ILEOSTOMY AARHUS UNIVERSITET (DK) 2025-04-10 WO disclosed
CN-118203627-A Application of elm-cape jasmine hemostatic granule in preparing medicine for preventing or treating inflammatory bowel disease 鲁南厚普制药有限公司 2024-06-18 CN disclosed
CN-115212273-B Application of Yinhua Miyanling pian in preparing medicament for treating ulcerative colitis 吉林华康药业股份有限公司 2023-09-01 CN disclosed
CN-108220417-B Quality control product of chromosome aneuploid detection kit capable of being stably stored and application 广州市金圻睿生物科技有限责任公司 2021-08-13 CN disclosed
CN-108048529-B Quality control product of lung cancer methylation gene detection kit capable of being stably stored and application 广州市金圻睿生物科技有限责任公司 2021-01-19 CN disclosed
WO-1997030051-A1 ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 1997-08-21 WO disclosed
WO-1997030052-A1 SYNTHESIS OF ACYCLIC NUCLEOSIDES MEDIVIR AB (SE) 1997-08-21 WO disclosed
CN-1125393-A Novel therapeutic delivery systems IMARX PHARMACEUTICAL CORP (US) 1996-06-26 CN disclosed
CN-1116238-A Method for cultiating tomato with function of anti virus of mosaic of cucumber by gene engineering UNIV BEIJING (CN) 1996-02-07 CN disclosed
CN-1090929-A The immunoassay of isothiazolones ROHM & HAAS (US) 1994-08-17 CN disclosed
CN-1037173-A The protein of inducing bone to generate COLLAGEN CORP (US) 1989-11-15 CN disclosed