Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 2/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL29703771 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL2120554 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL29365913 | 1.00 | — | — | |
| Purine SCHEMBL30862524 | 1.00 | — | — | |
| Purine SCHEMBL3158 | 1.00 | — | — | |
| Purine SCHEMBL6438164 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL31212689 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL619820 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL712798 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL31628309 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005089128-A2 | RAPID IDENTIFICATION OF MICROBIAL AGENTS | ISIS PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| WO-1997039352-A1 | ASSAYS FOR DETECTION OF PURINE METABOLITES | FOX CHASE CANCER CENTER (US) | 1997-10-23 | — | — | WO | disclosed |
| CN-2098720-U | PUZZLE DOOR BELL | WANG ZHENHAI (CN) | 1992-03-11 | — | — | CN | disclosed |