Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 12/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.58 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389606 | 1.00 | HSP90AB1 (0.71) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL28932207 | 0.89 | HSP90AB1 (0.61) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL3395507 | 0.89 | HSP90AB1 (0.74) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL3394076 | 0.87 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL3821565 | 0.87 | YTHDC1 (0.57) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL29366555 | 0.86 | HSP90AA1 (0.54) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL14441142 | 0.86 | HSP90AB1 (0.54) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL5471657 | 0.86 | HSP90AA1 (0.54) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 | |
| SCHEMBL3392226 | 0.85 | HSP90AB1 (0.77) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL21977307 | 0.85 | HDAC6 (0.69) | HSP90AB1HSP90AA1ADORA2AHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993870-B | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113993870-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-01-28 | — | — | CN | disclosed |