Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471657 | 1.00 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1ADORA2ACDK1HPGD | |
| SCHEMBL3821565 | 0.88 | YTHDC1 (0.57) | HSP90AA1HSP90AB1ADORA2AHPGDCTSL | |
| SCHEMBL14441142 | 0.87 | HSP90AB1 (0.54) | HSP90AA1HSP90AB1ADORA2AHPGDCTSL | |
| SCHEMBL29366455 | 0.86 | HSP90AB1 (0.71) | HSP90AA1HSP90AB1ADORA2AHDAC6HDAC4 | |
| SCHEMBL3389606 | 0.86 | HSP90AB1 (0.71) | HSP90AA1HSP90AB1ADORA2AHDAC6HDAC4 | |
| SCHEMBL5461518 | 0.86 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1ADORA2AHPGDCTSL | |
| SCHEMBL5462682 | 0.84 | CTSL (0.59) | HSP90AA1HSP90AB1CDK1CTSL | |
| SCHEMBL5456480 | 0.83 | PDE4A (0.54) | HSP90AA1HSP90AB1ADORA2AHPGDCTSL | |
| SCHEMBL12857135 | 0.82 | YTHDC1 (0.57) | HSP90AA1HSP90AB1CDK1YTHDC1HDAC6 | |
| SCHEMBL16774386 | 0.82 | ADORA2A (0.49) | HSP90AA1HSP90AB1ADORA2AHPGDCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993870-B | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113993870-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-01-28 | — | — | CN | disclosed |