SCHEMBL29367155

SCHEMBL29367155

C=C1C(=O)OC2CC(C)C(C(CC(C)=O)OC(C)=O)=CCC12

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KDR P35968 1/20 0.52
▸ MAPT P10636 3/20 0.34
▸ RAB9A P51151 3/20 0.34
▸ PKM P14618 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ PTGS2 P35354 2/20 0.33
▸ NPC1 O15118 2/20 0.32
▸ XBP1 P17861 2/20 0.32
▸ HTT P42858 2/20 0.32
▸ MDM2 Q00987 2/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ AGTR1 P30556 1/20 0.32
▸ PAX8 Q06710 1/20 0.32
▸ GPR55 Q9Y2T6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28537740 0.79 KDR (0.34) KDRPTGS2
Tomentosin SCHEMBL29422245 0.73 KDR (0.58) KDRMAPTRAB9APKMRECQL
Tomentosin SCHEMBL10028477 0.73 KDR (0.58) KDRMAPTRAB9APKMRECQL
SCHEMBL28619917 0.72 MAPT (0.37) KDRMAPTRAB9APKMRECQL
SCHEMBL2553256 0.68 KDR (1.00) KDRMAPTRAB9APKMRECQL
SCHEMBL10028473 0.68 KDR (0.51) KDRMAPTRAB9APKMRECQL
SCHEMBL29665914 0.57 TAS2R46 (0.56) KDRMAPTRAB9APKMRECQL
SCHEMBL9240777 0.56 MAPT (0.43) KDRMAPTRAB9APKMRECQL
SCHEMBL29410309 0.56 MAPT (0.43) KDRMAPTRAB9APKMRECQL
SCHEMBL8629536 0.56 MAPT (0.43) KDRMAPTRAB9APKMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701406-A1 GENETIC DETERMINANTS CONFERRING IMPROVED TOBRFV RESISTANCE Vilmorin & Cie (FR) 2026-03-04 — — EP disclosed
WO-2024223900-A1 GENETIC DETERMINANTS CONFERRING IMPROVED TOBRFV RESISTANCE VILMORIN & CIE (FR) 2024-10-31 — — WO disclosed
WO-2024223901-A1 RESISTANCE TO TOMATO BROWN RUGOSE FRUIT VIRUS AT ELEVATED TEMPERATURES VILMORIN & CIE (FR) 2024-10-31 — — WO disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
US-11883436-B2 Method of preparing hematopoietic stem and progenitor cells for transplantation THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-01-30 — — US disclosed
US-20230365657-A1 SECRETION OF HEME-CONTAINING POLYPEPTIDES IMPOSSIBLE FOODS INC. 2023-11-16 — — US disclosed
CN-115867250-A Skin tightening cosmetic compositions and methods of use 莱雅公司 2023-03-28 — — CN disclosed
CN-111714494-B Application of compound regulator in regulating metabolic disorder caused by artemisinin sensitive/resistant plasmodium infection 扬州大学 2022-08-26 — — CN disclosed
EP-3459950-B1 TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES JINGBO AGROCHEMICALS TECH CO LTD (CN) 2022-05-18 — — EP disclosed
EP-3459951-B1 TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES JINGBO AGROCHEMICALS TECH CO LTD (CN) 2022-05-11 — — EP disclosed
US-20220047639-A1 Method of Preparing Hematopoietic Stem and Progenitor Cells for Transplantation THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2022-02-17 — — US disclosed
CN-108588263-B Method for positioning and cloning double recessive genes for controlling same character in plant 中国农业科学院烟草研究所 2022-02-01 — — CN disclosed
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