Tomentosin

Tomentosin

SCHEMBL29422245

C=C1C(=O)O[C@H]2C[C@H](C)C(CCC(C)=O)=CC[C@H]12

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDR P35968 1/20 0.58
▸ MAPT P10636 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ PKM P14618 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ NPC1 O15118 1/20 0.36
▸ XBP1 P17861 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ MDM2 Q00987 1/20 0.36
▸ PTGS2 P35354 2/20 0.35
▸ NLRP3 Q96P20 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tomentosin SCHEMBL10028477 1.00 KDR (0.58) KDRMAPTRAB9APKMRECQL
SCHEMBL10028473 0.82 KDR (0.51) KDRMAPTRAB9APKMRECQL
SCHEMBL2553256 0.73 KDR (1.00) KDRMAPTRAB9APKMRECQL
SCHEMBL29367155 0.73 KDR (0.52) KDRMAPTRAB9APKMRECQL
SCHEMBL16202801 0.62 LMNA (0.35) —
Carabrone SCHEMBL30046035 0.61 NLRP3 (0.40) MAPTRAB9ANPC1XBP1HTT
SCHEMBL29410309 0.60 MAPT (0.43) KDRMAPTRAB9APKMRECQL
SCHEMBL8629536 0.60 MAPT (0.43) KDRMAPTRAB9APKMRECQL
SCHEMBL9240777 0.60 MAPT (0.43) KDRMAPTRAB9APKMRECQL
SCHEMBL9242953 0.60 MAPT (0.43) KDRMAPTRAB9APKMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146282-A1 QUANTIFICATION OF NUCLEIC ACIDS AND/OR ASSESSMENT OF THE STATUS OF NUCLEIC ACID DEGRADATION AND/OR INTEGRITY BY DIGITAL PCR QIAGEN GMBH (DE) 2026-05-28 — — US disclosed
EP-4735632-A1 HIGH-ACCURACY QUANTIFICATION OF NUCLEIC ACIDS FROM PRE-DEFINED AMOUNTS OF CELLS USING PLATE-BASED DIGITIAL PCR QIAGEN GmbH (DE) 2026-05-06 — — EP disclosed
EP-3516072-B1 METHOD FOR QUANTIFYING AND/OR DETECTING HUMAN MALE DNA QIAGEN GMBH (DE) 2026-05-06 — — EP disclosed
EP-3512962-B1 METHOD AND KIT FOR DETERMINING NUCLEIC ACID DEGRADATION QIAGEN GMBH (DE) 2026-02-11 — — EP disclosed
US-20260007131-A1 HERBICIDAL COMPOSITION CONTAINING DIFLUOROBUTENOIC ACID AMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2026-01-08 — — US disclosed
US-20250380696-A1 METHOD FOR CONTROLLING UNDESIRED PLANTS AND PROMOTING GROWTH OF USEFUL PLANTS ISHIHARA SANGYO KAISHA, LTD. (JP) 2025-12-18 — — US disclosed
EP-4638790-A1 METHOD OF NUCLEIC ACID QUANTIFICATION USED TO INCREASE DYNAMIC RANGE IN DIGITAL PCR QIAGEN GmbH (DE) 2025-10-29 — — EP disclosed
EP-4608990-A1 QUANTIFCATION OF NUCLEIC ACIDS AND/OR ASSESSMENT OF THE STATUS OF NUCLEIC ACID DEGRADATION AND/OR INTEGRITY BY DIGITAL PCR QIAGEN GmbH (DE) 2025-09-03 — — EP disclosed
EP-4608991-A1 DIGITAL AMPLIFICATION METHOD FOR QUANTIFYING AND/OR DETERMINING INTEGRITY OF HUMAN MALE DNA QIAGEN GmbH (DE) 2025-09-03 — — EP disclosed
EP-4581154-A1 FREEZE DRIED NUCLEIC ACID AMPLIFICATION MIXTURE QIAGEN GmbH (DE) 2025-07-09 — — EP disclosed
US-11384383-B2 In vitro isolation and enrichment of nucleic acids using site-specific nucleases DEPIXUS (FR) 2022-07-12 — — US disclosed
US-20220211041-A1 HERBICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2022-07-07 — — US disclosed
US-20220202018-A1 HERBICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2022-06-30 — — US disclosed
EP-4018000-A1 COMPOSITION AND METHOD FOR AMPLIFICATION OF STR LOCI QIAGEN GmbH (DE) 2022-06-29 — — EP disclosed
EP-4010494-A1 RNA SEQUENCING METHOD FOR THE ANALYSIS OF B AND T CELL TRANSCRIPTOME IN PHENOTYPICALLY DEFINED B AND T CELL SUBSETS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-06-15 — — EP disclosed
US-11345952-B2 Internal amplification control QIAGEN GMBH (DE) 2022-05-31 — — US disclosed
EP-3837379-B1 METHOD OF NUCLEIC ACID ENRICHMENT USING SITE-SPECIFIC NUCLEASES FOLLOWED BY CAPTURE DEPIXUS (FR) 2022-05-18 — — EP disclosed
US-20220145357-A1 METHOD OF NUCLEIC ACID ENRICHMENT USING SITE-SPECIFIC NUCLEASES FOLLOWED BY CAPTURE DEPIXUS (FR) 2022-05-12 — — US disclosed
EP-3977857-A1 HERBICIDE COMPOSITION Ishihara Sangyo Kaisha, Ltd. (JP) 2022-04-06 — — EP disclosed
US-20220025451-A1 KIT FOR DETERMINING NUCLEIC ACID DEGRADATION QIAGEN GMBH (DE) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146282-A1 QUANTIFICATION OF NUCLEIC ACIDS AND/OR ASSESSMENT OF THE STATUS OF NUCLEIC ACID DEGRADATION AND/OR INTEGRITY BY DIGITAL PCR DNTT, POLL, GDA KDR 4205/4885MAPT 3357/4885RAB9A 4187/4885
US-20260007131-A1 HERBICIDAL COMPOSITION CONTAINING DIFLUOROBUTENOIC ACID AMIDE COMPOUND DDT, CBR1, DHCR24 KDR 1824/4885MAPT 4537/4885RAB9A 1057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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