Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.78 |
| ▸ | TSHR | P16473 | 7/20 | 0.78 |
| ▸ | HPGD | P15428 | 6/20 | 0.78 |
| ▸ | AHR | P35869 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731778 | 0.94 | HSD17B10 (0.68) | HSD17B10TSHRHPGDAHRMAPK1 | |
| SCHEMBL9732416 | 0.89 | AHR (0.67) | HSD17B10TSHRHPGDAHRMAPK1 | |
| Triclofenol SCHEMBL29387498 | 0.88 | HSD17B10 (1.00) | HSD17B10TSHRHPGDAHRMAPK1 | |
| Triclofenol SCHEMBL1338 | 0.88 | HSD17B10 (1.00) | HSD17B10TSHRHPGDAHRMAPK1 | |
| Triclofenol SCHEMBL2813598 | 0.85 | HSD17B10 (0.93) | HSD17B10TSHRHPGDAHRMAPK1 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL29367365 | 0.82 | AHR (1.00) | HSD17B10TSHRHPGDAHRMAPK1 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 | 0.82 | AHR (1.00) | HSD17B10TSHRHPGDAHRMAPK1 | |
| SCHEMBL48305 | 0.82 | HSD17B10 (0.86) | HSD17B10TSHRHPGDMAPK1CYP3A4 | |
| SCHEMBL69259 | 0.78 | HSD17B10 (0.80) | HSD17B10TSHRHPGDAHRMAPK1 | |
| SCHEMBL10357236 | 0.77 | HSD17B10 (0.67) | HSD17B10TSHRHPGDMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794168-B1 | USING MONOOXYGENASE ENZYME P450CAM; MAY BE CARRIED OUT IN CELLS, ANIMALS OR PLANTS; FOR REDUCING ENVIRONMENTAL POLLUTION | ISIS INNOVATION LIMITED (GB) | 2004-09-21 | — | — | US | disclosed |
| EP-1190067-A1 | PROCESS FOR OXIDISING AROMATIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2002-03-27 | — | — | EP | disclosed |
| US-6204005-B1 | ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER | ECOCHEM RESEARCH, INC. | 2001-03-20 | — | — | US | disclosed |
| WO-2000078973-A1 | PROCESS FOR OXIDISING AROMATIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2000-12-28 | — | — | WO | disclosed |
| US-5538852-A | QUALITATIVE OR QUANTITATIVE ANALYSIS WITH COMPETITORS AND ANTIBODIES | ECOCHEM RESEARCH, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5145790-A | Immunoassay, fluorescein derivative | ABBOTT LABORATORIES (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0455058-A2 | Reagents and method for detecting polychlorinated biphenyls | ABBOTT LABORATORIES (US) | 1991-11-06 | — | — | EP | disclosed |