Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 11/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366112 | 1.00 | AHR (0.67) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| SCHEMBL30034845 | 0.88 | CYP3A4 (0.67) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| SCHEMBL2230314 | 0.88 | CYP3A4 (0.67) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL29367365 | 0.82 | AHR (1.00) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 | 0.82 | AHR (1.00) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| SCHEMBL4453545 | 0.79 | AHR (0.60) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| SCHEMBL29624841 | 0.79 | AHR (0.60) | AHRMAPK1CYP3A4HPGDHSD17B10 | |
| SCHEMBL29366530 | 0.79 | AHR (0.60) | AHRMAPK1CYP3A4HSD17B10TSHR | |
| SCHEMBL4459622 | 0.79 | AHR (0.60) | AHRMAPK1CYP3A4HSD17B10TSHR | |
| Pentachlorobenzene SCHEMBL11455164 | 0.78 | CYP3A4 (1.00) | AHRMAPK1CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220351865-A1 | METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS | GERO PTE. LTD. (SG) | 2022-11-03 | — | — | US | claimed |
| CN-115248258-A | Preparation and detection method of to-be-detected sample of polychlorinated biphenyl in packaging material | 湖南中烟工业有限责任公司 | 2022-10-28 | — | — | CN | claimed |
| EP-3881907-A1 | METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION | Université de Lille (FR) | 2021-09-22 | — | — | EP | claimed |
| EP-3188743-B1 | TREATMENT OF HEPATIC AND CEREBRAL TOXICITY CAUSED BY AT LEAST ONE POLLUTANT | UNIV GRENOBLE ALPES (FR) | 2020-11-18 | — | — | EP | claimed |
| CN-111665313-A | Method for determining polychlorinated biphenyl compounds in aquatic products | 孟祥龙 | 2020-09-15 | — | — | CN | claimed |
| CN-115820621-A | Carbon-based microbial inoculum for synchronously degrading halogenated organic matters and passivating heavy metals as well as preparation method and application thereof | 华南理工大学 | 2023-03-21 | — | — | CN | disclosed |
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
| CN-113311083-B | Method for determining seven indicative polychlorinated biphenyls in fish scales | 广东产品质量监督检验研究院（国家质量技术监督局广州电气安全检验所、广东省试验认证研究院、华安实验室） | 2022-12-16 | — | — | CN | disclosed |
| CN-111308003-B | Method for simultaneously detecting diisopropylnaphthalenes, polychlorinated biphenyls, phthalate compounds and photoinitiator | 福建中烟工业有限责任公司 | 2022-11-08 | — | — | CN | disclosed |
| US-20220351865-A1 | METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS | GERO PTE. LTD. (SG) | 2022-11-03 | — | — | US | disclosed |
| CN-115248258-A | Preparation and detection method of to-be-detected sample of polychlorinated biphenyl in packaging material | 湖南中烟工业有限责任公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-113945650-A | Method for simultaneously analyzing persistent organic pollutants in grains | 国家粮食和物资储备局科学研究院 | 2022-01-18 | — | — | CN | disclosed |
| EP-1616022-A2 | TEST SYSTEM FOR DETECTING CONTAMINANTS | Crown Vision Systems Limited (GB) | 2006-01-18 | — | — | EP | disclosed |
| US-20050148097-A1 | Instruments for detecting low-molecular weight substance | ENBIOTEC LABORATORIES C., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1489420-A1 | INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE | Enbiotec Laboratories Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004090156-A2 | TEST SYSTEM FOR DETECTING CONTAMINANTS | CROWN VISION SYSTEMS LIMITED (GB) | 2004-10-21 | — | — | WO | disclosed |
| US-20030054424-A1 | Rapid and sensitive method for measuring PCB contamination | HYBRIZYME | 2003-03-20 | — | — | US | disclosed |
| US-6469187-B1 | PREPARATION OF FISH OIL WITH REDUCED PCBS BY A PROCESS OF COLD CLEARING, MIXING WITH ACTIVATED CHARCOAL UNDER REDUCED PRESSURE AND FILTRATION | MERCK PATENT GMBH (DE) | 2002-10-22 | — | — | US | disclosed |
| US-4276179-A | Removing halogenated hydrocarbons from aqueous media by utilizing a polyolefinic microporous adsorbent | CELANESE CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4246255-A | Disposal of PCB | ROCKWELL INTERNATIONAL CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | PFKFB3, PFKFB4, PFKFB1 | AHR 3353/4885MAPK1 1468/4885CYP3A4 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.