Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 12/20 | 0.44 |
| ▸ | RXRA | P19793 | 5/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 10/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528253 | 0.81 | RXRA (0.52) | CYP26A1RXRARXRGRXRBCYP26B1 | |
| SCHEMBL9770694 | 0.76 | RXRA (0.34) | CYP26A1RXRARXRGRXRBCYP26B1 | |
| SCHEMBL6148042 | 0.71 | CYP26A1 (0.71) | CYP26A1RXRARXRGRXRBCYP26B1 | |
| SCHEMBL585772 | 0.71 | RXRA (0.50) | RXRARXRGRXRB | |
| SCHEMBL29403030 | 0.71 | RXRA (0.50) | RXRARXRGRXRB | |
| SCHEMBL7940089 | 0.67 | TSHR (0.46) | CYP26A1RXRARXRGRXRBCYP26B1 | |
| SCHEMBL5199934 | 0.66 | HDAC4 (0.35) | CYP26A1RXRARXRGRXRBPOLB | |
| SCHEMBL6146899 | 0.65 | CYP26A1 (0.69) | CYP26A1RXRARXRGRXRBCYP26B1 | |
| SCHEMBL6146438 | 0.65 | RARA (0.51) | CYP26A1RXRARXRGRXRBCYP26B1 | |
| SCHEMBL6144438 | 0.65 | CYP26A1 (0.58) | CYP26A1RXRARXRGRXRBCYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215923-B | Macrocyclic broad-spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-115215923-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114007605-B | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114007605-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |