Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.34 |
| ▸ | RXRG | P48443 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665085 | 0.85 | GABRA1 (0.33) | RXRARXRGRXRB | |
| SCHEMBL28665083 | 0.78 | RXRA (0.48) | RXRARXRGRXRB | |
| SCHEMBL29367472 | 0.76 | CYP26A1 (0.44) | RXRARXRGRXRBCYP26A1CYP26B1 | |
| SCHEMBL9770721 | 0.73 | PDK2 (0.42) | RXRA | |
| SCHEMBL9770732 | 0.70 | ESR2 (0.38) | RXRARXRGRXRBCYP26A1CYP26B1 | |
| SCHEMBL5706904 | 0.70 | CDC25A (0.37) | — | |
| SCHEMBL29561052 | 0.68 | S1PR1 (0.31) | — | |
| SCHEMBL8981801 | 0.68 | RXRA (0.39) | RXRARXRGRXRBCYP26A1CYP26B1 | |
| SCHEMBL8366289 | 0.66 | RXRA (0.41) | RXRARXRGRXRBCYP26A1CYP26B1 | |
| SCHEMBL3176733 | 0.66 | RXRA (0.54) | RXRARXRGRXRBCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987261-A | Diaminoindane derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-01-22 | — | — | US | disclosed |