Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272180 | 0.82 | NOTUM (0.33) | SMN1; SMN2KIF11ABL1SRCPTK2 | |
| SCHEMBL2936753 | 0.80 | PIK3C3 (0.34) | SMN1; SMN2KIF11ABL1SRCBMP1 | |
| SCHEMBL270665 | 0.76 | BMP1 (0.38) | SMN1; SMN2HSP90AA1HSP90B1KIF11ABL1 | |
| SCHEMBL271739 | 0.74 | MAPT (0.34) | — | |
| SCHEMBL272015 | 0.73 | MRGPRX4 (0.36) | HSP90AA1HSP90B1 | |
| SCHEMBL271254 | 0.73 | GRM4 (0.38) | SMN1; SMN2HSP90AA1HSP90B1KIF11ABL1 | |
| SCHEMBL270928 | 0.72 | NOTUM (0.35) | KIF11ABL1SRCPTK2GRM4 | |
| SCHEMBL2373247 | 0.71 | GRM4 (0.38) | SMN1; SMN2HSP90AA1HSP90B1KIF11ABL1 | |
| SCHEMBL272109 | 0.70 | MAPT (0.37) | — | |
| SCHEMBL270522 | 0.70 | MRGPRX4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063180-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |