Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271739 | 0.91 | MAPT (0.34) | NOTUMMAPT | |
| SCHEMBL272015 | 0.90 | MRGPRX4 (0.36) | NOTUMMAPT | |
| SCHEMBL270665 | 0.88 | BMP1 (0.38) | PTK2RORCSMN1; SMN2KIF11KEAP1 | |
| SCHEMBL269838 | 0.85 | POLQ (0.38) | MAPT | |
| SCHEMBL270767 | 0.85 | NOTUM (0.34) | NOTUMPTK2 | |
| SCHEMBL271470 | 0.83 | NFE2L2 (0.33) | NOTUMPTK2SMN1; SMN2KIF11KEAP1 | |
| SCHEMBL272014 | 0.83 | NR1H2 (0.40) | — | |
| SCHEMBL2936752 | 0.82 | SMN1; SMN2 (0.34) | PTK2SMN1; SMN2KIF11ABL1SRC | |
| SCHEMBL2936753 | 0.81 | PIK3C3 (0.34) | PTK2SMN1; SMN2KIF11ABL1SRC | |
| SCHEMBL271653 | 0.81 | MAPT (0.33) | NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | NOTUM 234/4885PTK2 4647/4885RORC 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.