Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25659594 | 1.00 | JUN (0.35) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL4277492 | 0.81 | ATR (0.40) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL22791669 | 0.80 | ALDH1A1 (0.43) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL30371953 | 0.79 | ALDH1A1 (0.33) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL25659595 | 0.79 | ALDH1A1 (0.33) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL29906642 | 0.77 | TSHR (0.48) | ALDH1A1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL1669584 | 0.77 | TSHR (0.48) | ALDH1A1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL29364820 | 0.74 | HPGD (0.47) | ALDH1A1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL1667344 | 0.74 | HPGD (0.47) | ALDH1A1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8578654 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250064955-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | ADCENTRX THERAPEUTICS INC (US) | 2025-02-27 | — | — | US | disclosed |
| EP-4426299-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | Adcentrx Therapeutics Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023081232-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | ADCENTRX THERAPEUTICS INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-115215923-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114007605-B | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114007605-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250064955-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | ABCB1, DHFR, CD44 | JUN 4761/4885NFKB1 2899/4885NFKB2 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.