Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 8/20 | 0.43 |
| ▸ | PRKDC | P78527 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22712451 | 1.00 | IKBKB (0.47) | IKBKBASIC3COPS5DGAT1ATR | |
| SCHEMBL22712516 | 0.85 | IKBKB (0.44) | IKBKBASIC3DGAT1ATRPRKDC | |
| SCHEMBL29410008 | 0.85 | IKBKB (0.44) | IKBKBASIC3DGAT1ATRPRKDC | |
| SCHEMBL319167 | 0.83 | ASIC3 (0.57) | IKBKBASIC3ATRPRKDCATM | |
| SCHEMBL28175377 | 0.79 | DGAT1 (0.51) | IKBKBDGAT1PRKDCNPC1RAB9A | |
| SCHEMBL23703565 | 0.75 | PIK3CD (0.53) | ATRPRKDCATM | |
| SCHEMBL22732755 | 0.73 | DGAT1 (0.45) | IKBKBDGAT1PRKDCNPC1RAB9A | |
| SCHEMBL30048631 | 0.73 | ATR (0.67) | ATRPRKDCATM | |
| SCHEMBL23703073 | 0.73 | ATR (0.67) | ATRPRKDCATM | |
| SCHEMBL26941761 | 0.73 | DGAT1 (0.45) | DGAT1PRKDCNPC1RAB9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215923-B | Macrocyclic broad-spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-115215923-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114007605-B | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-3968983-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2022-03-23 | — | — | EP | disclosed |
| CN-114007605-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |